Weight Loss 99% High Quality Rimonabant Powder CAS 168273-06-1 From Biocar

RimonabantAdverse effects

Data from clinical trials submitted to regulatory authorities showed that rimonabant caused depressive disorders or mood alterations in up to 10% of subjects and suicidal ideation in around 1%, and in Europe it was contraindicated for people with any psychiatric disorder, including depressed or suicidal people.
Additionally, nausea and upper respiratory tract infections were very common (occurring in more than 10% of people) adverse effects; common adverse effects (occurring in between 1% and 10% of people) included gastroenteritis, anxiety, irritability, insomnia and other sleep disorders, hot flushes, diarrhea, vomiting, dry or itchy skin, tendonitis, muscle cramps and spasms, fatigue, flu-like symptoms, and increased risk of falling.

The FDA's advisory committee raised concerns that based on animal data, it appeared that the therapeutic window with regard to CNS toxicity, and specifically seizures was almost nonexistent; the therapeutic dose and the dose that caused seizures in animals appeared to be the same. When the EMA reviewed postmarketing surveillance data, it found that the risk of psychiatric disorders in people taking rimonabant was doubled.

Rimonabant Application

1) Obesity

In a 2006 (2 year) study reported in JAMA, "Compared with the placebo group, the 20 mg of rimonabant group produced greater mean (SEM) reductions in weight (-6.3 [0.2] kg vs -1.6 [0.2] kg; P<.001), waist circumference (-6.1 [0.2] cm vs -2.5 [0.3] cm; P<.001), and level of triglycerides (percentage change, -5.3 [1.2] vs 7.9 [2.0]; P<.001) and a greater increase in level of high-density lipoprotein cholesterol (percentage change, 12.6 [0.5] vs 5.4 [0.7]; P<.001)." [12]

2) Smoking cessation

Rimonabant may also be found to be effective in assisting some smokers to quit smoking. Sanofi is currently conducting studies to determine the possible value of rimonabant in smoking-cessation therapy. The Studies with Rimonabant and Tobacco Use (STRATUS) program involves more than 6,000 subjects.

Stratus is designed to explore two smoking-related therapies: first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers. Initial results apparently suggest rimonabant is effective for both uses. However, the FDA has explicitly stated to Sanofi that, without additional studies, rimonabant cannot be approved in the United States for smoking cessation therapy.

Wuhan Biocar Pharmaceutical Co., Ltd. is a high-tech innovative enterprise specializing in the R & D, production and sales of API and pharmaceutical intermediates (excluding drugs). Our company is based on the optical valley biological city, with the help of Wuhan University Scientific Research Laboratory, making full use of the park policy advantages, focusing on the research and development of biological medicine. Our company always adheres to the business philosophy of "market demand oriented; technology research and development as the core competitiveness; e-commerce as the platform", more accurate, better, faster and more reliable to provide biomedical products for pharmaceutical units, university scientific research institutions, hospital outpatient service, reagent units, distributors in the world.

Our Advantages
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.
FAQ
1.Q: Can i get some samples?
A:Yes, we can supply the free sample ,but the shipping cost be paid by customer.
2.Q:How to start orders or make payment?
A:You could use credit card.And we could also accept the bank transfer or Western Union,BTC,etc.
3.Q:How to confirm the Product Quality before placing orders?
A:We have complete QS system,and will provide the test report.You can get free samples for some products,you only need to pay the shipping cost.
4.Q:What's your MOQ?
A: Depending on the cost of product.
5.Q:How about delivery leadtime?
A:Within 2 working days after payment confirmed.
6.Q:How do you control the safety of your products ?
A:Control raw material to finished product, third party report.
7.Q:Is it field inspection available ?
A:Yes,we support field inspection.
8.Q:How long does it take to the goods arrived?
A:For 1KG-100KG, Within 5-7 days by DHL,UPS,TNT, FEDEX,EMS Over 100KG.within 5-8days by air,20-40days by sea.
9.Q:How about Customs clearance?Will you refund or reship if it is seized?
A: We have full of experience to do the customs clearance,generally it will have no trouble.And we will reship or refund for you if it is seized by our mistake.