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High Purity Olmesartan Medoxomil Powder CAS 144689-63-4

China High Purity Olmesartan Medoxomil Powder CAS 144689-63-4, Find details about China Olmesartan Medoxomil, CAS 144689-63-4 from High Purity Olmesartan Medoxomil Powder CAS 144689-63-4

Model NO.
VZ2020186
Product Name
Olmesartan Medoxomil
CAS
144689-63-4
Molecular Formula
C29h30n6o6
Molecular Weight
558.585
Einecs
604-433-1
Melting Point
180°c
Boiling Point
804.2±75.0 °c(Predicted)
Grade
Pharmaceutical Grade
Shelf Life
2 Years
Assay
98%Min
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Model NO.
VZ2020186
Product Name
Olmesartan Medoxomil
CAS
144689-63-4
Molecular Formula
C29h30n6o6
Molecular Weight
558.585
Einecs
604-433-1
Melting Point
180°c
Boiling Point
804.2±75.0 °c(Predicted)
Grade
Pharmaceutical Grade
Shelf Life
2 Years
Assay
98%Min
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Product NameOlmesartan Medoxomil
CAS144689-63-4
MFC29H30N6O6
MW558.585
storage temp.-20°C Freezer
AppearanceWhite powder
Assay98%min
High Purity Olmesartan Medoxomil Powder CAS 144689-63-4
Uses:
Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.

Olmesartan medoxomil is a pro-drug that is de-esterified to the active metabolite, olmesartan. Olmesartan has a dual method of elimination, with about 60% eliminated by the liver and the remainder by the kidney. In situations of impaired renal or hepatic function, the alternative excretion pathway can compensate for the compromised one. Olmesartan is not metabolized by the cytochrome P450 enzyme system and therefore has a low potential for metabolic drug interactions, a feature that may be of importance when treating patients on multiple drug regimens, such as the elderly. Olmesartan is well tolerated and has an excellent safety profile that is comparable to that of placebo. In addition, olmesartan provides 24-h blood pressure control with a once-daily dosing. In head-to-head studies, olmesartan delivered superior blood pressure reduction when compared with other angiotensin-II receptor antagonists at their recommended doses.

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