China GMP Standard Manufacturer Supply 99% Medicine Peptide Bpc157 Powder CAS: 137525-51-0, Find details about China Bpc 157, Pentadecapeptide from China GMP Standard Manufacturer Supply 99% Medicine Peptide Bpc157 Powder CAS: 137525-51-0
CAS NO | 137525-51-0 |
Synonyms | Bpc 15, Bpc-157, Booly protection compound 15 |
Molecular Formula | C62H98N16O22 |
Molecular Weight | 1419.53552 |
Appearance | White Powder |
Purity | 99.5% |
Certification | GMP, ISO 9001, USP |
Standard | Pharma grade |
Usage | Pharmaceutical intermediates |
Source Chemical | Synthesis |
Storage | Lyophilized BPC 157 is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting BPC 157 should be refrigerated at temperatures not to exceed 36 F. |
BPC 157 (Pentadecapeptide) has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease.
bpc 157 (pentadecapeptide) was shown to accelerate wound healing and to have a marked angiogenic effect.In addition, it significantly facilitates the healing of bone fracture in rats.
This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect.
BPC 157 ( Body Protection Compound-157) Is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice. Experiments have shown that BPC 157 enhances the healing of wounds, Including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon. The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157. These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration. The results revealed that the explants' Outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157. Also, A MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon. However, Results also showed that BPC 157 significantly increased the survival of cells under oxidative stress. Furthermore, The Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion. Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner.
Item | Specification | Result | |
Appearance | White powder | Complies | |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% | 0.2% 0.06% | |
Odor | Characteristic | Complies | |
Assay | 99% | 99.22% | |
Heavy Metal | <10ppm | Complies | |
As | <0.1ppm | 0.05ppm | |
Pb | <0.1ppm | 0.05ppm | |
Cd | <0.1ppm | 0.05ppm | |
Residual Solvents | <100ppm | Complies | |
Residual Pesticide | Negative | Complies | |
Total Plate Count | <1000cfu/g | Complies | |
Yeast & Mold | <100cfu/g | Complies | |
E.Coli | Negative | Complies | |
Salmonella | Negative | Complies |
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FAQ
Q1: Can I get a sample?
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Q2: What is your MOQ?
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