7, 8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7, 8-Dhf 99% CAS 38183 -03-8

China 7, 8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7, 8-Dhf 99% CAS 38183-03-8, Find details about China 38183-03-8, 7 8-Dihydroxyflavone from 7, 8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7, 8-Dhf 99% CAS 38183-03-8

Model NO.
38183-03-8
Shelf Life
Two Years
Usage
Pharmaceutical Intermediates
Type
Pharmaceutical Intermediates
Payment Ways
Western Union, Money Gram, Paypal and T/T
Delivery Time
Within 24 Hours After Payment
Grade
Pharmaceutical Grade
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2934999091
Model NO.
38183-03-8
Shelf Life
Two Years
Usage
Pharmaceutical Intermediates
Type
Pharmaceutical Intermediates
Payment Ways
Western Union, Money Gram, Paypal and T/T
Delivery Time
Within 24 Hours After Payment
Grade
Pharmaceutical Grade
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2934999091
7,8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7,8-DHF 99% Cas 38183-03-8 
 
Basic Info
 

Poduct Name:7,8-Dihydroxyflavone
Synonyms:7,8-dihydroxy-2-phenyl-4h-chromen-4-one
CAS No.:38183-03-8
Appearance:Yellow Powder
Purity(HPLC):≥99%
MW:254.24

product function:
1. 7-8-dihydroxyflavone  is widely used in food, beverage, pharmaceutical, cosmetic and other industries.
2. 7-8-dihydroxyflavone powder is a perfect colorant used in wine, beverage, syrup, jam, ice cream, pastry and so on.

It has been found to act as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally-bioavailable and able to penetrate the blood-brain-barrier

Description

7,8-dihydroxyflavone (7,8-DHF) is a synthetic flavonoid that was initially discovered in a study screening for small molecules that could activate a particular receptor known as tropomyosin-related kinase B (TrkB), because the peptide produced in the human body that acts on this receptor, called brain derived neurotrophic factor (BDNF), could not be used due to poor absorption into the brain. 7,8-DHF was found to be a potent mimic of BDNF able to act on TrkB in a similar manner. This means that 7,8-DHF could theoretically cause similar effects as BDNF in the brain, and in theory be more therapeutically useful due to its better absorption and ability to cross the blood-brain barrier.

Application / dosage

 

There are currently no human studies on 7,8-DHF to take human doses from, with all estimates being mathematically approximated from rodent research. The majority of rodent research does use intravenous injections however, with limited studies using oral ingestion.

Oral ingestion does appear to have effects, with rat studies noting:
5mg/kg being effective in the cognitively unwell mouse (chronic usage)
10mg/kg being effective in the cognitively well rat (subchronic use)
30mg/kg in the mouse being acutely effective

This is approximately 1mg/kg for subchronic or chronic usage in humans, with the acute dose correlating to approximately 2.5mg/kg.


7, 8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7, 8-Dhf 99% CAS 38183-03-8

Packing

· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
7, 8-Dihydroxyflavone API Pharmaceutical Grade Raw Materials 7, 8-Dhf 99% CAS 38183-03-8


SHIPPING ADVISE

 By Express
Sultable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to plck up the goods.
 By Air
Sultable for more than 50 kg, Fast: 4-5 days, HIgh cost, alrport to alrportprofesslonal broker needed.
 By sea
Sultable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, protesslonal broker needed.


FAQ

Q1: Can i get small sample?
A: Yes, FREE SAMPLES of some products can be sent on request, but the shipping cost be paid by our customers.
Q2. How to confirm the products quality before placing orders?
A: COA first for you to check the specification,and we test every batch of our product
by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party
lab such as SGS,PONY etc.  

Q3: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Money Gram. Also L/C at sight is acceptable for large amount

Why Choose Us
  1. We have 10 years of experience in exporting products, strong market response capabilities and a wide range of trading partners.
  2. We have a variety of certified factories to produce high quality products.
  3. We offer full link hosted services from production to delivery.
  4. We provide testing services prior to shipment of the product.
  5. We will cultivate customers in every country market, let customers develop quickly with us, and win-win cooperation.
  6. Stable supply, delivery on time, quality assurance.