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High Purity 7 8-Dihydroxyflavone Powder CAS 38183 -03-8

China High Purity 7 8-Dihydroxyflavone Powder CAS 38183-03-8, Find details about China 7 8-Dihydroxyflavone, CAS 38183-03-8 from High Purity 7 8-Dihydroxyflavone Powder CAS 38183-03-8

Model NO.
VZ2020025
Product Name
7 8-Dihydroxyflavone
CAS
38183-03-8
Molecular Formula
C15h10o4
Molecular Weight
254.24
Einecs
253-812-4
Appearance
Yellow Powder
Grade
Medical Grade
Shelf Life
2 Years
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Model NO.
VZ2020025
Product Name
7 8-Dihydroxyflavone
CAS
38183-03-8
Molecular Formula
C15h10o4
Molecular Weight
254.24
Einecs
253-812-4
Appearance
Yellow Powder
Grade
Medical Grade
Shelf Life
2 Years
Transport Package
Bag/Drum
Specification
0.01Kg~5Kg/bag
Origin
Hubei, China
Product Name
7,8-DIHYDROXYFLAVONE
CAS No
38183-03-8
EINECS
253-812-4
MF
C15H10O4
MW
254.24
Boiling Point
494.4±45.0 °C(Predicted)
Melting Point
243-246°C

High Purity 7 8-Dihydroxyflavone Powder CAS 38183-03-8

Introduction:
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone
  7,8-DHF is both orally bioavailable and able to penetrate the blood-brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease.

Function and Application:
   7,8-DHF has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome.
   7,8-DHF also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents.
   In addition, 7,8-DHF possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.



 

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