China Veterinary Antibiotic Bulk Ceftiofur Sodium Sterile Powder 104010-37-9 Ceftiofur Sodium, Find details about China Ceftiofur Sodium Powder, Ceftiofur Sodium Purity from Veterinary Antibiotic Bulk Ceftiofur Sodium Sterile Powder 104010-37-9 Ceftiofur Sodium
Ceftiofur sodium is a cephalosporin antibiotic for veterinary clinical use and a broad-spectrum antibacterial drug. It has strong antibacterial effect on gram-positive bacteria and gram-negative bacteria.
Product Name | Ceftiofur sodium |
CAS | 104010-37-9 |
Einecs No | 680-655-2 |
Appearance | White or grayish yellow powder |
MF | C19H18N5NaO7S3 |
Molecular Weight | 547.55 |
Purity | 99% min |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder |
Shelf Life | 24 Months |
TEST | SPECIFICATION | RESULT | |
Character | White or grayish yellow powder,odor free and humidifying | Conform | |
Identification | 1. In the chromatogram of the assay, the retention time of the principal peak in the chromatogram obtained with the test solution corresponds to that of the principal peak in the chromatogram obtained with reference solution 2. It gives flame reaction of sodium salt | Conform | |
Water | Not more than 3.0% | 0.71% | |
Acidity(pH) | 5.5~7.5 | 6.2 | |
Color of solution | No more intensity colored than reference solution Yedllow 9 or Orange-yellow 9 | Less intensely colored than reference solution Yellow 8 | |
Clarity of solution | No more pronounced than that of reference suspension I | Less pronounced than that of reference suspension I | |
Assay (Ceftiofur sodium) | No less than 98.0%(anhydrous and aceton free) | 98.8% | |
Related substances | Biggest individual impurity | No more than 0.5% | 0.1% |
Total | No more than 3.0% | 0.98% | |
Residual solvents | Aceton: no more than 2.0% | 1.0% | |
Particulate matter | ≥10μm:no more than 5000 particles/g | 597 particles/g | |
≥25μm:no more than 500 particles/g | 27 particles/g | ||
Bacterial endotoxin | No more than 0.2EU/mg (Ceftiofur) | Less than 0.20EU/mg(Ceftiofur) | |
Sterility | No growth of micro-organisms should occur after 14 days of incubation | No growth of micro-organisms should occur after 14 days of incubation |
Ceftiofur has a broad antibacterial spectrum and strong antibacterial activity. It has strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and some anaerobic bacteria. Among them, Gram-positive bacteria are similar to or similar to the first-generation cephalosporins. It is weak and has strong antibacterial activity against Gram-negative bacteria such as Escherichia coli, Salmonella, Pasteurella, etc. It is suitable for the respiratory tract and urinary tract infections caused by various sensitive bacteria, especially for the prevention and treatment of early death of chicken fry caused by Escherichia coli, Salmonella, Pseudomonas aeruginosa, Staphylococcus, etc., and E. coli in piglets at the age of 1 day. Yellow diarrhea and wound infections caused by cutting the umbilical cord, ear punching, cutting teeth, cutting tails, etc., as well as porcine pleuropneumonia caused by Actinobacillus haemophilus, bronchopneumonia in cattle, etc.
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