Quinine HCL Powder is an alkaloid of cinchona that was once widely used to control and prevent malaria; it also has analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and it decreases the excitability of the motor end plate. It is used as the dihydrochloride, hydrochloride, or sulfate salt in the treatment of resistant falciparum malaria.

Quinine HCL Powder can cause abnormal heart rhythms, and should be avoided if possible in patients with atrial fibrillation, conduction defects or heart block. Quinine can cause hemolysis in G6PD deficiency (an inherited deficiency), but this risk is small and the physician should not hesitate to use quinine in patients with G6PD deficiency when there is no alternative.

Function:

It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. emeraldgo(at)hotmail.com.

Quinine HCL is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.