Anti -Ob Cadherin Rabbit Primary Polyclonal Antibody
China Anti -Ob Cadherin Rabbit Primary Polyclonal Antibody, Find details about China Primary Antibody, Primary Antibodies from Anti -Ob Cadherin Rabbit Primary Polyclonal Antibody
Anti -OB Cadherin Rabbit Primary Polyclonal Antibody for Research
Product Information| Description | OB Cadherin rabbit polyclonal |
| Protein full name | Cadherin-11 |
Synonyms | OSF-4, Cdh11, Cad-11, Osteoblast cadherin, OB-cadherin |
| Immunogen | Recombinant protein corresponding to Mouse OB Cadherin |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 88 kDa |
Observed MW. | 120 kDa |
| Uniprot ID | P55287, P55288 |
Applications
| Applications | WB |
| Species | Human, Mouse, Rat |
| Dilution | 1: 500-1: 1000 |
| Positive tissue | lung, uterus |
Background
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-11 (OB-Cadherin) is a marker of the loosely connected and migratory cellular elements of the mesenchyme. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. Recently, Cadherin-11 mRNA and protein were found to be expressed in most invasive breast cancer cell lines tested but not in non-invasive cell lines, suggesting that Cadherin-11 may be a marker for aggressive, invasive tumor subsets.
Images
| Western blot analysis of OB Cadherin (GB111278) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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