China High Quality Raw Powder Estrone with CAS 53-16-7, Find details about China Pharmaceutical Intermediate, Pharmaceutical Chemical from High Quality Raw Powder Estrone with CAS 53-16-7
Estrone CAS: 53-16-7
Appearance: White or almost white crystalline powder Assay:
NLT 99.0% Standard: EP/ USP Sandard
Aplication: Synthetic medicine ethinylestradiol intermediate
Packing: 1kg/aluminum tin; 25kg/carton barrel.
Storage: Protect from humidity; keep in a dry, cool, and shady place. Remarks: Only for chemical products.
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase. Function: a) Estrone is mainly as intermediate of Ethinyl Estradiol. b) Estrone is one of Several Natural Estrogens, which also include estriol and estradiol. Estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy.
*Certificate of Analysis*
Item | Standard | Test Results | |
Loss on drying | ≤2.0% | 0.19% | |
Heavy metals | ≤10 ppm | <10ppm | |
Water | ≤1.0% | 0.1% | |
Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% | |
Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% |
Total Impurity | ≤0.5% | 0.18% | |
Purity | ≥99.0% | 99.7% | |
Assay | 99.0%~101.0% (anhydrous substance). | 99.8% | |
Microbiological Analysis | |||
Total plate count | ≤1000cfu/g | Complies | |
Salmonella | Absent | Negative | |
Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies |
Other product:
benzocaine | 94-09-7 |
Procaine | 59-46-1 |
Procaine Hydrochloride | 51-05-8 |
tetracaine | 94-24-6 |
tetracaine hydrochloride | 136-47-0 |