Amoxicillin  Capsule
character
This product is a capsule, and its content is white or almost white powder.

indication
Amoxicillin is suitable for the following infections caused by sensitive bacteria (non beta lactamase producing strains)
1. Upper respiratory tract infections such as otitis media, sinusitis, pharyngitis and tonsillitis caused by Streptococcus haemolyticus, Streptococcus pneumoniae, Staphylococcus or Haemophilus influenzae.
2. Urogenital tract infection caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis.
3. Skin and soft tissue infection caused by hemolytic streptococcus, Staphylococcus or Escherichia coli.
4. Acute bronchitis, pneumonia and other lower respiratory tract infections caused by hemolytic streptococcus, Streptococcus pneumoniae, Staphylococcus or Haemophilus influenzae.
5. Acute simple gonorrhea.
6. This product can also be used in the treatment of typhoid, typhoid carrier and leptospirosis; amoxicillin can also be combined with clarithromycin and lansoprazole to eradicate Helicobacter pylori in stomach and duodenum and reduce the recurrence rate of peptic ulcer.

Usage and dosage
Oral administration. 5 g for adults, once every 6-8 hours, daily dose not more than 4 G.
The daily dose for children is 20-40 mg / kg, once every 8 hours; the daily dose for infants under 3 months is 30 mg / kg, once every 12 hours.
The dosage should be adjusted in patients with severe renal impairment. The patients with endogenous creatinine clearance rate of 10-30ml / min had 0.25-0.5g every 12 hours, and the patients with endogenous creatinine clearance rate of less than 10ml / min had 0.25-0.5g every 24 hours.

Adverse reactions
1. Nausea, vomiting, diarrhea and pseudomembranous enteritis.
2. Allergic reactions such as rash, drug fever and asthma.
3. Anemia, thrombocytopenia, eosinophilia, etc.
4. Serum aminotransferase may be slightly increased.
5. Secondary infection caused by Candida or drug-resistant bacteria.
6. The central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior were occasionally seen.

taboo
Penicillin allergy and penicillin skin test positive patients are forbidden.

matters needing attention
1. Oral penicillins can cause anaphylactic shock, which is more common in patients with allergic history of penicillin or cephalosporin. The history of drug allergy must be inquired and penicillin skin test must be done before medication. In case of anaphylactic shock, the patients should be rescued on the spot, and treated with keeping airway smooth, oxygen inhalation, and glucocorticoid.
2. Patients with infectious mononucleosis are prone to skin rash and should be avoided.
3. Patients with long course of treatment should check liver and kidney function and blood routine.
4. Amoxicillin can lead to false positive in urine glucose test with Benedict or Fehling reagent.
5. The following situations should be used with caution:
(1) Patients with asthma, hay fever and other allergic diseases.
(2) The dosage may need to be adjusted when the elderly and renal function are seriously damaged.