China Top Quality CAS 78628-80-5 Terbinafine Hydrochloride, Find details about China Terbinafine Hydrochloride Powder, Terbinafine Hydrochloride Supply from Top Quality CAS 78628-80-5 Terbinafine Hydrochloride
Quick detail :
Product Name: Terbinafine Hydrochloride
CAS No.: 78628-80-5
EINECS No.: 245-385-8
Molecular Formula: C21H26ClN
Molecular Weight: 327.89
Appearance: White or off-white crystalline powder
Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.
Specification
ITEMS | SPECIFICATION |
Identification | Positive reaction |
PH | 4.5-6.0 |
Loss on drying | Not more than 0.75% |
Residue on ignition | Not more than 0.1% |
Chromatographic purity | Ranitidine Related Compound B not more than 0.5% |
Any other impurity not more than 0.3% | |
The sum of all impurities not more than 1.0% | |
Organic volatile impurities | Meets the requirements |
Residual solvents | Meets the requirements |
Assay(dry substance) | 97.5%-102.0% |
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