Posaconazole is used to treat invasive Aspergillus and Candida and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients. It is also used for the treatment of oropharyngeal candidiasis (OPC), including OPC refractory to itraconazole and/or fluconazole therapy.
Posaconazole is also used to treat invasive infections by Candida, Mucor, and Aspergillus species in severely immunocompromised patients.

Posaconazole has potent trypanocidal activity. Amiodarone acts synergistically with Posaconazole. Posaconazole also affects and disrupts Ca2+ homeostasis in T. cruzi. Posaconazole blocks the biosynthesis of ergosterol, which is essential for parasite survival. Posaconazole has a clear, dose-dependent effect on proliferation of the epimastigote (extracellular) stages, with a minimal inhibitory concentration of 20 nM and an IC50 of 14 nM. Against the clinically relevant intracellular amastigote form of the parasite, Posaconazole is even more potent.

Posaconazole has the minimal inhibitory concentration and IC50 values of 3 nM and 0.25 nM. Posaconazole is active against isolates of Candida and Aspergillus spp. that exhibit resistance to Fluconazole, Voriconazole, and Amphotericin B and is much more active than the other triazoles against zygomycetes

Other hot selling chemical product:
Egg Yolk Lecithin CAS 93685-90-6


Amphotericin B Powder Injection CAS 1397-89-3


Lidocaine Base 137-58-6


Valerophenone CAS 1009-14-9


2-Iodo-1-P-Tolylpropan-1-One Yellow Powder CAS 236117-38-7

Factory direct sale chemicals raw powder:

23239-88-5	Benzocaine hydrochloride
13956-29-1	Cbd
51-05-8	Procaine Hydrochloride
94-09-7	Benzocaine
14769-73-4	Tetramisole
137-58-6	Lidocaine
5086-74-8	Tetramisole  Hydrochloride
23076-35-9	Xylazine hydrochloride
5413-05-8	BMK Powder
1451-82-7	2-bromo-4-methylpropiophenone
59-46-1	Procaine
49851-31-2	2-Bromo-1-phenyl-1-pentanone
13605-48-6	Pmk Glycidate
5413-05-8	Ethyl 3-oxo-4-phenylbutanoate
236117-38-7	2-iodo-1-p-tolylpropan-1-one
102-97-6	Benzylisopropylamine

Related Chemical Raw Product:
Amphotericin B CAS 1397-89-3


Vitamin B4 Powder CAS 73-24-5


Egg Yolk Lecithin CAS 93685-90-6


Hspc Powder CAS 97281-48-6

 

LOWEST PRICE ketone to Russia, Kazakhstan, Ukraine: 

Packing: 
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).

Delivery:  

  1. Stock products are normally shipping within 3 working days. 

  2. For rush delivery, please contact our sales team for particular arrangement.

  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

  2. Shipping details & shipping documents will be provided and sent by email.

  3. We keep tracking the shippment until clients well received.

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

Company Information:

Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological  company integrating product research and development, manufacturing and tradi-ng of chemical intermediates, specialized in organic intermediates, pharmaceutical intermediates, chemical solvents and agrochemical products. We produce and provide fluffy powder, Alpha Bromovalerophenone, Valerophenone, Watermelon ketone and cocoylchloride, etc.

Since 2016, in response to the government guidance, we have been accelerating industrial restructure, enlarging the production capacity gradually. At present, we have over 600 employees, 29 technician; with 11 masters and 4 doctors. With all staffs' effort, Mulei is growing rapidly, products are exported to overseas countries, including Southeast Asia, Europe, North America and South America, well received by customers.

OUR FACTORY TOUR