99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351- 69 -6
China 99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6, Find details about China Everolimus, Rapamycin from 99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
Basic Info.
Model NO.
hupharma
Payment
Bitcoin/Wu/Mg/Wire Transfer
Minimum
10g
Delivery Time
1-3 Days
Shipping
Worldwide
Trademark
hupharma
Transport Package
Safe and Fast Delivery
Specification
10g, 100g, 1kg, 25kg
Origin
China
HS Code
2937290090
Model NO.
hupharma
Payment
Bitcoin/Wu/Mg/Wire Transfer
Minimum
10g
Delivery Time
1-3 Days
Shipping
Worldwide
Trademark
hupharma
Transport Package
Safe and Fast Delivery
Specification
10g, 100g, 1kg, 25kg
Origin
China
HS Code
2937290090
Product Desciption
99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
Product Name: Everolimus
Synonyms: Everolimus(mixture of isomers);Everolimus powder;CERTICAN; ZORTRESS; AFINITOR;Rapamycin, 42-O-(2-hydroxyethyl)-;Everolimus;Certican;CERTICAN(R);EveroliMus(RAD-001)
CAS: 159351-69-6
MF: C53H83NO14
MW: 958.22
EINECS: 621-003-9
Appearance: white powder
Uses: Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation
Uses: Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM
Uses: Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
Uses: Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations.
Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.
99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
99% Purity Everolimus Rapamycin Powder Sirolimus CAS 159351-69-6
Product Name: Everolimus
Synonyms: Everolimus(mixture of isomers);Everolimus powder;CERTICAN; ZORTRESS; AFINITOR;Rapamycin, 42-O-(2-hydroxyethyl)-;Everolimus;Certican;CERTICAN(R);EveroliMus(RAD-001)
CAS: 159351-69-6
MF: C53H83NO14
MW: 958.22
EINECS: 621-003-9
Appearance: white powder
Uses: Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation
Uses: Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM
Uses: Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
Uses: Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations.
Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.
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