China Pharmaceutical Intermediates Topiramate Powder CAS No. 97240-79-4, Find details about China Free Sample Topiramate, Quality Control Topiramate from Pharmaceutical Intermediates Topiramate Powder CAS No. 97240-79-4
Product Name: | Topiramate |
Other Name | MCN 4853, RWJ 17021 |
CAS: | 97240-79-4 |
MF: | C12H21NO8S |
MW: | 339.36 |
Purity: | 99% Min |
Shelf Life | 2 years |
Appearance | White crystalline powder |
Brand Name: | Oriherb |
Form | Powder |
Place of Origin: | Shaanxi, China (Mainland) |
Packaging: | Bottle, Can, Drum, Plastic Contain |
Standard: | USP EP JP etc. |
Introduction: | Topiramate is an anticonvulsant that antagonizes GluR5 receptors (IC50 = 0.46 μM) and acts as a positive allosteric modulator of GABAA receptor-mediated currents. This compound inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. |
1.Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay. 2.This drug has been investigated for use in treating alcoholism,methamphetamine addiction,and obesity, especially to reduce binge eating. 3.This drug is also widely used to treat migraines due to the effect it has on the blood vessels in the brain 4.The drug is also used in clinical trials to treat post traumatic stress disorder 5.And recently. clinical reports indicate that it may have mood stabilizing properties.
Applied in Pharmaceutical field
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