Factory Supply High Quality High Purity Topiramate Powder CAS 97240-79-4 Cheap Price Whole Price 99% Purity
China Factory Supply High Quality High Purity Topiramate Powder CAS 97240-79-4 Cheap Price Whole Price 99% Purity, Find details about China Topiramate, Wholesale Topiramate from Factory Supply High Quality High Purity Topiramate Powder CAS 97240-79-4 Cheap Price Whole Price 99% Purity
Basic Info.
Model NO.
Topiramate
Solubility
DMSO: ~44mg/Ml
Water Solubility
9.705g/L
Merck
14, 9547
Density
1.336±0.06 g/cm3
Boiling Point
438.7±55.0 °c
Storage Conditions
2-8ºC
Trademark
TMH
Transport Package
Plastic Bag or Bottle
Specification
42*42*52
Origin
Guangdong, China
Model NO.
Topiramate
Solubility
DMSO: ~44mg/Ml
Water Solubility
9.705g/L
Merck
14, 9547
Density
1.336±0.06 g/cm3
Boiling Point
438.7±55.0 °c
Storage Conditions
2-8ºC
Trademark
TMH
Transport Package
Plastic Bag or Bottle
Specification
42*42*52
Origin
Guangdong, China
Product Desciption
Topiramate CAS 97240-79-4 Anticonvulsant Active Pharmaceutical Ingredients
Topiramate Description:
Topiramate (the TPM) is a naturally existing monosaccharide D-fructose sulfide, and together with felbamate, lamotrigine and vigabatrin are current several broad-spectrum anti-epileptic drugs with relatively wide clinical application and can be used to control different types of epilepsy with excellent efficacy and pharmacokinetics.
This product is generally used for the adjuvant treatment of antiepileptic drugs and is effective in treating simple and complex seizures as well as systemic tonic-clonic seizures and can also be used for the treatment of infantile spasms. Features of this product include excellent long-term efficacy, no significant resistance as well as being able to be used alone for antiepileptic purpose.
But in cases of being applied to children or fast increase of the amount can cause cognitive impairment and neurotoxicity, and easy to trigger kidney stones.
Topiramate Ptoduct Application:
In 1980, scientists had first successfully synthesized topiramate in the laboratory. It had been applied to patients with epilepsy for the first time in 1986. In 1995, it was approved for entering into the market of UK for the first time. Its basic structure is fructopyranose sulfamate. Unlike other kinds of anti-epileptic drug, TPM has various kinds of anti-epileptic mechanisms including blocking the voltage-dependent sodium channels, enhancing the activity of GABA in the location of the γ- aminobutyric acid A (GABAA) receptor as well as blocking the activity of the AMPA glutamate receptor. In addition, there is still mild effect of carbonic anhydrase inhibitors.
Europe and the United States had conducted double-blind, placebo-controlled studies and demonstrated that the adjunctive therapy with topiramate has excellent efficacy, safety and is well tolerated in the treatment of various types of refractory epilepsy. Now it has begun with topiramate monotherapy and has also achieved good results with 62% of patients with epileptic seizures disappearing completely.
Our Advantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
Delivery:
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitate you track the express
FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.
| Product name | Topiramate |
| CAS NO. | 97240-79-4 |
| MF | C12H21NO8S |
| MW | 339.36 |
| EINECS | 200-659-6 |
| Appearance | White Powder |
| Usage | 1. anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor. 2. Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. |
| Properties of topiramate | |
| melting point | 125°C |
| Specific rotation | D23 -34.0° |
| boiling point | 438.7±55.0 °C(Predicted) |
| density | 1.336±0.06 g/cm3(Predicted) |
| flash point | 9ºC |
| Storage conditions | 2-8°C |
| solubility | DMSO: ~44 mg/mL |
| Acidity coefficient (PKA) | 9.22±0.70(Predicted) |
| Color | white |
| Water solubility | 9.705g/L(temperature not stated) |
| Merck | 14,9547 |
| EPA chemical information | .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate (97240-79-4) |
Topiramate Description:
Topiramate (the TPM) is a naturally existing monosaccharide D-fructose sulfide, and together with felbamate, lamotrigine and vigabatrin are current several broad-spectrum anti-epileptic drugs with relatively wide clinical application and can be used to control different types of epilepsy with excellent efficacy and pharmacokinetics.
This product is generally used for the adjuvant treatment of antiepileptic drugs and is effective in treating simple and complex seizures as well as systemic tonic-clonic seizures and can also be used for the treatment of infantile spasms. Features of this product include excellent long-term efficacy, no significant resistance as well as being able to be used alone for antiepileptic purpose.
But in cases of being applied to children or fast increase of the amount can cause cognitive impairment and neurotoxicity, and easy to trigger kidney stones.
Topiramate Ptoduct Application:
In 1980, scientists had first successfully synthesized topiramate in the laboratory. It had been applied to patients with epilepsy for the first time in 1986. In 1995, it was approved for entering into the market of UK for the first time. Its basic structure is fructopyranose sulfamate. Unlike other kinds of anti-epileptic drug, TPM has various kinds of anti-epileptic mechanisms including blocking the voltage-dependent sodium channels, enhancing the activity of GABA in the location of the γ- aminobutyric acid A (GABAA) receptor as well as blocking the activity of the AMPA glutamate receptor. In addition, there is still mild effect of carbonic anhydrase inhibitors.
Europe and the United States had conducted double-blind, placebo-controlled studies and demonstrated that the adjunctive therapy with topiramate has excellent efficacy, safety and is well tolerated in the treatment of various types of refractory epilepsy. Now it has begun with topiramate monotherapy and has also achieved good results with 62% of patients with epileptic seizures disappearing completely.
Our Advantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
Delivery:
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitate you track the express
FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.
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