Name: Paclitaxel
CAS#: 33069-62-4
Molecular formula: C47H51NO14
Molecular weight: 264.36 
Specification: 99.5%
Origin: China
Appearance: White crystalline powder
Odour : Characteristic
Particle size: 100% pass 80 mesh
Shelf Life: Two years

Taxol is a monomer diterpenoid compound extracted from Natural Plant Taxus bark, is a kind of complex secondary metabolites, is currently understood only a drug can promote microtubule polymerization and stability of microtubules have been aggregated. Isotope tracing showed that paclitaxel was bound only to polymerized microtubules, not to the polymerized tubulin two. Cell contact paclitaxel after the accumulation of a large number of microtubules in cells, which interfere with microtubule accumulation of various cellular functions, especially the cell division stop in mitosis, blocking the normal cell division. Paclitaxel is mainly used in ovarian cancer and breast cancer, and has a certain effect on lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma and brain tumors.
The good effect of refractory ovarian cancer and breast cancer treatment of ovarian cancer and platinum have become resistant to treatment, prostate cancer, head and neck cancer, esophageal cancer, germ cell tumors, endometrial carcinoma, lymphoma, bladder cancer, gastrointestinal cancer, small cell and non-small cell lung cancer with good prospects. Precipitation of acicular crystalline or amorphous powder from methanol. Melting point 213~216 DEG C (decomposition). [alpha]D20-49 degrees (methanol). UV maximum absorption (methanol):227273nm (epsilon 298001700). A broad spectrum of antineoplastic drugs used in ovarian cancer, breast cancer, etc.. A broad spectrum of antineoplastic drugs used in the treatment of ovarian cancer, breast cancer and other diseases. For the treatment of metastatic breast cancer and metastatic ovarian cancer. A broad spectrum of antineoplastic drugs used in the treatment of ovarian cancer, breast cancer and other diseases

1.Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.