High Quality 6805-41-0 Horse Chestnut Extract Escin Aescin
China High Quality 6805-41-0 Horse Chestnut Extract Escin Aescin, Find details about China Aescin, Escin from High Quality 6805-41-0 Horse Chestnut Extract Escin Aescin
Basic Info.
Model NO.
6805-41-0
Product Name
Aescin
CAS Number
6805-41-0
Inci
Escin
Molecular Weight
1131.26 G/Mol
Molecular Formula
C55h86o24
Appearance
White or Light-Yellow Powder
Particle Size
98% Through 80 Mesh
Extract Solvent
Water & Ethanol
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
98%
Origin
China
Model NO.
6805-41-0
Product Name
Aescin
CAS Number
6805-41-0
Inci
Escin
Molecular Weight
1131.26 G/Mol
Molecular Formula
C55h86o24
Appearance
White or Light-Yellow Powder
Particle Size
98% Through 80 Mesh
Extract Solvent
Water & Ethanol
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
98%
Origin
China
Product Desciption
1. Aescin Overview
Aescin, also known as Escin, Horse Chestnut Extract, is a pentacyclic triterpenoid saponin. It is a mixture of several structurally similar isomers; and the components are not easily separated. Aescin is derived from dried seeds of horse chestnut. It is crystalline powder. Aescin is hardly soluble in water, slightly soluble in cold alcohol; and it is soluble in ethanol and so on. We develops two specifications Aescin: 98% and 20%. Both of them are 100% natural cosmetic raw materials.
Aescin, as a saponin compound, is a surfactant, as well as of a strong foaming ability. It can be used as a detergent and foaming agent. Additionally, Aescin exerts anti-inflammatory effect. It can alleviate skin allergies; and it can prevent and treat skin erythema, inflammation and allergies. Moreover, Aescin can promote blood circulation. It promotes wound healing, and possesses anti-edema property. Thus it can be used in cosmetics for removing eye dark circles, anti-redness, anti-wrinkle, and repairing skin.
2. Aescin Source
Horse chestnut (Latin name: Aesculus chinensis Bunge), also known as conker tree, is a deciduous plant of Sapindaceae family. Its seed is close to spherical; color is chestnut brown. The seed can be eaten after cooking with alkaline water. Also it can be used for medicinal purpose. The artificial cultivation area of horse chestnut is mainly distributed in the Yellow River Basin and the eastern provinces of China. The Qinling Mountains has wild distribution. It generally grows in mountains below 700 meters above sea level. The fruit of horse chestnut contains a large number of saponin compounds, mainly Aescin. And its seed is rich in fatty oil, crude protein, fiber, starch, etc; it is a traditional Chinese medicine. The seed is mainly used for cosmetics.
3.Specifications
Aescin 98% Specifications
Aescin 20% Specifications
Aescin 98% chromatogram
4. Aescin Manufacturer Flow Chart
5. Aescin Benefits
1.Anti-redness
Aescin can fill small gaps in tiny veins and finely visible gaps. Thereby, it effectively reduces vascular permeability, and improves integrity of vessel wall. Aescin is helpful to repair capillaries. Therefore, Aescin can be used to repair facial redness.
2.Anti-Inflammation
Aescin has an inhibitory effect on activity of phospholipase A2. Phospholipase A2 is not only involved in cell transmembrane information transmission, but also a key enzyme in production of inflammation and allergic mediators. Therefore, Aescin shows a certain anti-inflammatory property. It can relieve allergic skin, and prevent moisture accumulation in tissues. Also it quickly eliminates the heavy feeling and pressure caused by local edema. Aescin can remove eye edema and dark circles.
6. Study on the Pharmacology of Aescin and Cosmetics
Aescin, also known as Escin, Horse Chestnut Extract, is a pentacyclic triterpenoid saponin. It is a mixture of several structurally similar isomers; and the components are not easily separated. Aescin is derived from dried seeds of horse chestnut. It is crystalline powder. Aescin is hardly soluble in water, slightly soluble in cold alcohol; and it is soluble in ethanol and so on. We develops two specifications Aescin: 98% and 20%. Both of them are 100% natural cosmetic raw materials.
Aescin, as a saponin compound, is a surfactant, as well as of a strong foaming ability. It can be used as a detergent and foaming agent. Additionally, Aescin exerts anti-inflammatory effect. It can alleviate skin allergies; and it can prevent and treat skin erythema, inflammation and allergies. Moreover, Aescin can promote blood circulation. It promotes wound healing, and possesses anti-edema property. Thus it can be used in cosmetics for removing eye dark circles, anti-redness, anti-wrinkle, and repairing skin.| Product Name | CAS Number | INCI | |
| Aescin | 6805-41-0 | ESCIN | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 1131.26 g/mol | C55H86O24 |  | |
Horse chestnut (Latin name: Aesculus chinensis Bunge), also known as conker tree, is a deciduous plant of Sapindaceae family. Its seed is close to spherical; color is chestnut brown. The seed can be eaten after cooking with alkaline water. Also it can be used for medicinal purpose. The artificial cultivation area of horse chestnut is mainly distributed in the Yellow River Basin and the eastern provinces of China. The Qinling Mountains has wild distribution. It generally grows in mountains below 700 meters above sea level. The fruit of horse chestnut contains a large number of saponin compounds, mainly Aescin. And its seed is rich in fatty oil, crude protein, fiber, starch, etc; it is a traditional Chinese medicine. The seed is mainly used for cosmetics.
3.Specifications| Product Name | Specification |
| Aescin | 20%, 98% |
| Items | Specification |
| Assay(Titration) | ≥98.0% |
| Appearance | Almost white or light-yellow powder |
| Extract solvent | Water & ethanol |
| Physical Characteristics | |
| Particle size | 98% through 80 mesh |
| Moisture | ≤5.00% |
| Ash content | ≤5.00% |
| Rotation | -24.0~-30.0 |
| pH value | 3~5 |
| Solvent residue | European standard |
| Heavy Metals | |
| Heavy metals | ≤10ppm |
| Arsenic | ≤2ppm |
| Microbiological Tests | |
| Total Plate count | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Escherichia coli | Negative |
| Salmonella | Negative |
| Items | Specification |
| Assay | ≥20.0% |
| Appearance | Fine powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Extract solvent | Water & ethanol |
| Drying method | Spraying drying |
| Physical Characteristics | |
| Particle size | 98% through 80 mesh |
| Moisture | ≤5.00% |
| Ash content | ≤5.00% |
| Solvent residue | European standard |
| Heavy Metals | |
| Heavy metals | ≤10ppm |
| Arsenic | ≤2ppm |
| Plumbum | ≤2ppm |
| Microbiological Tests | |
| Total Plate count | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Escherichia coli | Negative |
| Salmonella | Negative |
4. Aescin Manufacturer Flow Chart
5. Aescin Benefits1.Anti-redness
Aescin can fill small gaps in tiny veins and finely visible gaps. Thereby, it effectively reduces vascular permeability, and improves integrity of vessel wall. Aescin is helpful to repair capillaries. Therefore, Aescin can be used to repair facial redness.
2.Anti-Inflammation
Aescin has an inhibitory effect on activity of phospholipase A2. Phospholipase A2 is not only involved in cell transmembrane information transmission, but also a key enzyme in production of inflammation and allergic mediators. Therefore, Aescin shows a certain anti-inflammatory property. It can relieve allergic skin, and prevent moisture accumulation in tissues. Also it quickly eliminates the heavy feeling and pressure caused by local edema. Aescin can remove eye edema and dark circles.
6. Study on the Pharmacology of Aescin and Cosmetics
| Test item | Concentration | Result |
| Promotion to ATP production by cell culture | 0.5μg/mL | Promotion rate:143.6 ( blank 100) |
| Inhibition to phospholipase A2 activity | 0.5μg/mL | Inhibition rate:36.3% |
| Inhibition to swelling of rat toes | 0.075% | Inhibition rate:58.6% |
| Inhibition to granulation swelling of cotton ball in rats | 0.5mg/kg | Inhibition rate:20.1% |
| Inhibition to IL-1βproduction induced by LPS | 0.1mg/mL | Inhibition rate:20.1% |
| Inhibition to activity of hyaluronidase | IC50:(149.9±2.6)μmol/L |
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