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Factory Supply Enramycin for Veterinary Use CAS#11115-82-5

China Factory Supply Enramycin for Veterinary Use CAS#11115-82-5, Find details about China Enramycin, Factory Supply Enramycin from Factory Supply Enramycin for Veterinary Use CAS#11115-82-5

Model NO.
dy-2020
Purity
99%
Grade
Pharmaceutical Grade
Origin
He Nan
HS Code
2942000000
Model NO.
dy-2020
Purity
99%
Grade
Pharmaceutical Grade
Origin
He Nan
HS Code
2942000000



Factory Supply Enramycin for Veterinary Use CAS#11115-82-5Product description                   

Enramycin is a polypeptide antibiotic that binds unsaturated fatty acids to more than a dozen amino acids. The main components are Enramycin A and B, which are its hydrochloride forms. application. White or yellowish white powder(coarse gray or gray-brown powder with extra odor). 234 ~ 238 °C decomposition, soluble in dilute hydrochloric acid, slightly soluble in water, methanol, ethanol, insoluble in acetone.


Function                                    


Enramycin has a strong activity against Gram-positive bacteria, especially Clostridium in the intestine. After long-term use, it is not easy to develop drug resistance because it changes the bacterial population in the intestine. Therefore, the use of nutrients in feed is good, which can promote weight gain in pigs and chickens and increase feed conversion rates. Enramycin oral LD50 was 10g per kilogram of weight in large mice and 522.9 mg in 4 weeks of age. However, Enramycin(crude crystal) used for feed addition was oral, 11 g per kg of body weight in rats and mice and 8 g in broilers. Teratogenic and mutagenicity tests were negative. After oral administration, Enramycin only plays a role in the digestive tract and is not easily absorbed. After 6 to 12 H of administration of the chicken, enramycin excreted in the faeces reached 87.0 % to 100 %, and the residue of the piglets was very small. After 1 week of continuous use, the residue in the tissues was less than 25 μg / kg on the same day. Enramycin has no toxic effect on crops, fish and the environment after it is discharged by chickens and pigs. Therefore, it is a safe and effective animal specific antibiotic. Enramycin is preserved at 40 °C for 4 months, and the price is still above 90 %, but the price is reduced when the humidity is high. Enramycin is stored at room temperature for 12 weeks in the added feed, and the potency is not less than 90 %.

 

Appliction                                    

 

1) Enramycin has a strong effect on Gram-positive bacteria. The main mechanism is to inhibit the synthesis of bacterial cell walls. The bacterial cell wall is mainly to maintain the appearance and maintain osmotic pressure stability. Its main component is viscous peptides. In Gram-positive bacteria, viscous peptides account for 65-95 % of the total cell wall. Enramycin can prevent the synthesis of sticky peptides, causing cell wall defects, causing intracellular osmotic pressure to increase, extracellular fluids to infiltrate the bacteria, causing bacteria to deform and swell, rupture and die. Enramycin mainly acts on the cracking stage of bacteria, not only sterilizing but also dissolving bacteria. The minimum antibacterial concentration is 0.05-3.13 μg / ml
2) The antibacterial ability of Enramycin to Clostridium aeruginosa is common in feeds. It can damage the small intestine, aggravate the severity of coccidiasis, and reduce the production performance of livestock and poultry. It is one of the main causes of chicken water stool, necrotizing enteritis and porcine diarrhea, and has become a universal concern in the world. It was found that Enramycin had the strongest antibacterial ability and no resistant strains were found in the test of Clostridium aeruginosa isolated from chicken farm by several progrowth antibiotics.

COA                                         
pH
pH value 5.0-7.2
5.7
Complies
Tyramine
Complies
complies
Complies
Loss on drying
Not more than 4.2%
2.4%
Complies
Residue on ignition
Not more than 2.5%
0.23%
Complies
Heavy metals
Not more than 20ppm
Less than 20ppm
Complies
Content of Tylosin
Tylosins A≥82%
89%
Complies
Tylosins A+B+C+D≥95%
97%
Complies
Assay
Assay (dried basis)
≥830u/mg(dried basis)
928u/mg (dried basis)
Complies
Assay (wet basis)
-
906u/mg (wet basis)
Complies
Conclusion
Tested according to in-house specification QS-0002-01, it complies with the requirements



                        Company profile                              
Factory Supply Enramycin for Veterinary Use CAS#11115-82-5


Packing                                           

25kgs/Fiber drum outside and plastic bag inside; 

1-25kgs packaging, aluminium Foil bag outside and double plastic bag inside;
Delivery Detail: within 3 days when get the payment
Shipping: We have  Professional  shipping agent, based on customers ' demand for transport
By express: FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR
Our Service:                                     
24 hours online 
1.Any inquiries will be replied with in 12 hours.

2.Dedication to quatity,supply& service.

3.Strictly on selecting raw meterials.

4.Reasonable & competitive price ,fast lead time.

5.Smple order in stock and one week for bulk production.

6. We have strong cooperation with FEDEX,TNT,DHL,EMS,or you also can choose your own shipping agent..
Factory Supply Enramycin for Veterinary Use CAS#11115-82-5





 

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