High Purity Silodosin Pharmaceutical Raw Materials CAS 160970-54-7 for Benign Prostatic Hyperplasia
China High Purity Silodosin Pharmaceutical Raw Materials CAS 160970-54-7 for Benign Prostatic Hyperplasia, Find details about China Silodosin, 160970-54-7 from High Purity Silodosin Pharmaceutical Raw Materials CAS 160970-54-7 for Benign Prostatic Hyperplasia
Basic Info.
Model NO.
CAS 160970-54-7
CAS
160970-54-7
Appearance
White Crystalline Powder
Mf
C25h32f3n3o4
Test
HPLC
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Application
Pharmaceutical Intermediates
Trademark
HH
Transport Package
1kg Per Foil Bag, 20kg Per Drum
Specification
99%
Origin
Nanjing
HS Code
2933990099
Model NO.
CAS 160970-54-7
CAS
160970-54-7
Appearance
White Crystalline Powder
Mf
C25h32f3n3o4
Test
HPLC
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Application
Pharmaceutical Intermediates
Trademark
HH
Transport Package
1kg Per Foil Bag, 20kg Per Drum
Specification
99%
Origin
Nanjing
HS Code
2933990099
Product Desciption
What is Silodosin?
Silodosin is a kind of α- adrenergic receptor antagonists developed by Japanese Kissei pharmaceutical company. It has a very good therapeutic efficacy on treating the dysuria related to benign prostatic hyperplasia. The selective effect on urethra of Silodosin is 12 times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent inhibition bladder activity excitation in the benign prostatic hypertrophy models of rats, and can also improve the pressure threshold of bladder contraction. These data have suggested that, in addition to helping improve bladder function, silodosin is also effective in alleviating the related symptoms associated with benign prostatic hypertrophy.
Silodosin is a kind of α- adrenergic receptor antagonists developed by Japanese Kissei pharmaceutical company. It has a very good therapeutic efficacy on treating the dysuria related to benign prostatic hyperplasia. The selective effect on urethra of Silodosin is 12 times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent inhibition bladder activity excitation in the benign prostatic hypertrophy models of rats, and can also improve the pressure threshold of bladder contraction. These data have suggested that, in addition to helping improve bladder function, silodosin is also effective in alleviating the related symptoms associated with benign prostatic hypertrophy.
1.Silodosin Got a good solve the curative effect of dysuria, also reduced the incidence of hypotension and other adverse reactions.
2.Silodosin can reduce peripheral vascular resistance in other parts of the body to the body of the systolic blood pressure and diastolic pressure is lower
2.Silodosin can reduce peripheral vascular resistance in other parts of the body to the body of the systolic blood pressure and diastolic pressure is lower
| Product Name | Silodmin | ||
| Reference | USDMF standard | ||
| Test Items | Specifications | Results | |
| Appearance | White or almost white crystalline powder. | White crystalline powder | |
| Identification | 1)The Infrared absorption spectrum of the substance to be examined shall comply with that obtained by Silodosin reference standard | Conform | |
| 2) The retention time of the major peak in the chromatogram of the Test solution corresponds to that in the chromatogram of the Reference solution.as obtained in the Isomer | Conform | ||
| Water | ≤0.5% | 0.1% | |
| Residue on ignition | ≤0.1% | <0.1% | |
| Assay (HPLC) | 98.0%~102.0% (Anhydrous and solvent-free substance) | 99.8% | |
| Isomer(HPLC) | ≤0.15% | <LOD(LOD:0.02%) | |
| Related substances (HPLC) | ImpurityA≤0.15% | 0.05% | |
| lmpurityB≤0.15% | <LOD(LOD:0.02%) | ||
| Any unidentified impurity≤0.10% | <LOD(LOD:0.02%) | ||
| Total impurities≤0.5% | 0.05% | ||
| Residual solvents (GC) | Toluene≤890ppm | <LOD(LOD:3ppm) | |
| EthanolW5000ppm | <LOD(LOD:8ppm) | ||
| Isopropyl acetate≤5000 ppm | <LOD(LOD:12ppm) | ||
| lsopropanol^5000ppm | <LOD(LOD:9ppm) | ||
| Heptane≤5000ppm | 268ppm | ||
| Dimethyl sulfoxide≤5000ppm | <1ppm | ||
| Residual Reagent | Pd≤10ppm | <LOD(LOD:1ppm) | |
| Pt≤10ppm | <LOD(LOD:1ppm) | ||
| Conclusion | Complies with USDMF standard | ||
Q1:Can you give me a discount price? A1:Sure, it depends on your quantity. |
Q2: What about the lead time? A2:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity. |
Q3:How do you control the quality? A3:We will make samples before mass production, and after sample approved, we will begin bulk production. |
Q4:How do you ship the goods and how long does it take to arrive? A4:We usually ship by UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional. |
Q5:What is you terms of payment? A5:Our normal payment term is T/T 30% deposit after order signed and 70% before shippment. |
Q6:Is there cheap shipping cost to import to our country? A6:For small order, express will be best. And for bulk order, sea ship way is best but take much time. |
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