China API Powder CAS 19982-08-2 Memantine Purity Memantine Powder Memantine, Find details about China Memantine, Memantine Powder from API Powder CAS 19982-08-2 Memantine Purity Memantine Powder Memantine
Product Name | Memantine |
CAS | 19982-08-2 |
Appearance | White crystalline powder |
MF | C12H21N |
MW | 179.3 |
Purity | 99% |
Shelf Life | 2 Years |
Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.
Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.
Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.