Semi Auto Liquid Based Cytology Processor

Model: MC-2000

 

Introduction

The specimen is diluted to reduce its viscosity, the non-diagnostic debris is filtered by membrane and diagnostic material remain, a thin layer of even cells is made automatically. It's very easy to discern this kind of slices, which improves the accuracy and positive rate greatly.

The instrument utilizes the mechanical,pneumatic and hydrodynamic theories for cell dispersion,collection and transfer.Rotation of drive breaks up the specimen softly.The pneumatic & hydrodynamic systems controlled by microprocessor supervise cell collection.Air pressure controlling,cell natural adhesion and high quality membrane are contributed to cells being transferred successfully.The whole process is highly automated. 

Features
Patented Technology
The patented technology is used to demount the Filter automatically, the Filter is discharged into Collection Vial to avoid the secondary pollution.
Muti-point Control
The system can identify the presence of Collection Vial, Filter and slide which ensures the success ratio of slide process. The alarm device on Waste Bottle will alarm when the bottle is full.
Stable
The structure of instrument are patented which makes the stable transfer of cells and the evener cell thin layer without white slides.
Convenient
Simple and automated operation procedures. The preparation time of each slide is less than 2 minutes, it's reproducible for the same specimen.
Intelligent
With 5 inches large LCD screen the operation procedures are indicated synchronously which is convenient to be observed. Pressure controllers supervise the system pressure effectively, which can both prevent membranes from breaking and collect diagnostic material. Memory function is available, even if blackout happens, the operation will not be interfered. 

Informatizational
Scientific report system was verified on market, it's convenient to print, save and check records.

Applicable
Slide process & staining of cell specimen prior to pathological analysis.

Ancillary Reagent Kit

Specimen Collection Brush
Removable soft brush head is convenient to collect specimens without injuring, the collected cells are no less than 5000.

Cell Preservative Solution
With cell encapsulation techniques 100% cells are preservable. It has special formula and can decompose mucus and distribute cells evenly.

Filter
Imported filter membranes are applied, the diameters and density of membrane hole are tested strictly which ensures quantity & quality of collected cells.

Anti Fall-off Slide
Through silicified process the slides have the charges to capture the lesion cells without white slides and cells falling.

Clinical Details
Exfoliative Cytology
The exfoliating cells from various body regions, especially the surface of luminal organ, are stained and observed under microscopes, ccordingly the diagnosis is made. This kind of laboratory medical science is called as exfoliative cytology, also as clinical cytology or cellular pathology.

The Source of Exfoliating Cells
Spontaneous discharge (sputum, urine, nipple discharge etc.) Cavity aspiration (pleural effusion,abdominal dropsy,aquae pericardii, brain effusion) Needle aspiration (soft tissue mass, mammary gland, lymphonodus, thyroid gland etc.)

Morphological Features of Malignant Cells
Caryon atypia: caryons become big and are malformed, the stained caryones are darken and crude, the proportion of caryon & cytoplasm is abnormal, the plasmosomes increase in size and quantity, mitotic figures increase, tumor giant cells and bare nucleus appear.
Cytoplasm atypia: rich highly differentiating malignant cell cytoplasm; little poorly differentiated one. 
Cell distribution: without polarity and in chaos.
Slide background :with lots of neutrophile granulocytes, lymphocytes, phagocytes, erythrocytes etc.

Conventional Cytology Diagnosis Technique
Conventional cytology diagnosis technique plays positive role in prior screening and diagnosis. However the examination method is quite simple, it's difficult to collect the cell specimens fully. The manual slide processing has large randomness which causes cells multi-layer overlap and morphological variation. The method has limitations and uncertainty and it's possible that the false negative happens (it's reported that there are 2% to 5% false negative from many cervical slides), some patients with cervical carcinoma missed diagnosis. The false negative causes cervical carcinoma patients miss the chance of early treatment and suffer great misery.

Liquid-based Thin-layer Slide Technique
Non-diagnostic debris is removed through special techniques. The clear thin-layer slide is prepared and easy to be observed and accuracy of diagnosis is improved obviously. It's classified into two types, membrane type (TCT) and sedimentation type (LCT), according to difference of working principles.

TCT Operation Procedures (Membrane Type)
1. Cervical brush stirs in little bottle about tens of seconds the exfoliating cells are washed into cell preserve solution.
2. The non-diagnostic debris is filtered by high precision membrane.
3. Thin-layer cells with diameter 20mm are made on defined position of the glass slide.
4. Fix it with 95% ethanol, pathologists evaluate it under microscopes after staining and sealing.
5. Analyze it with TBS diagnosis analysis system and print results finally.



Text-image System
1. The interface is artistic and easy to operate.
2. With the functions of image collection,process and comparison.
3. Powerful record management function.
4. Reports standardized,multi-formats available.