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Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918 -61-1

China Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1, Find details about China Raw Material, Chemical from Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1

Classification
Endocrine System Agents
Function
Prevention and Treatment of Shpt
Appearance
Powder
Type
Vitamins, Amino Acids and Coenzymes
Trademark
IKNOW
Specification
Content99%
Origin
China
Classification
Endocrine System Agents
Function
Prevention and Treatment of Shpt
Appearance
Powder
Type
Vitamins, Amino Acids and Coenzymes
Trademark
IKNOW
Specification
Content99%
Origin
China
Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1

What is vitamin D Derivative Drugs?

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.
Description

Paricalcitol was launched as Zemplar in the US for the prevention and treatment of secondary hyperthyroidism associated with chronic renal failure. Paricalcitol is a synthetic vitamin D2, namely a novel 1-alpha-hydroxy-19-noranalogue in which the ring A exocyclic methylene group, typical of all vitamin D systems, has been replaced by two hydrogen atoms. Paricalcitol is the first vitamin D analogue marketed for this indication. In patients with chronic renal failure, Paricalcitol appreciably reduced levels of parathyroid hormone (PTH) without a significant difference in the incidence rate for hypercalcemia or hyperphosphatemia when compared with placebo. 
 
Product Name:Paricalcitol
Synonyms:PARICALCITOL (10 MG)F0E3030.997MG/MG(AI);
19-nor-1alpha,25-dihydroxyvitamin D2;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;
Zemplar;
CAS:131918-61-1
Molecular Structure:Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1
AppearanceWhite or off-white powder
MF:C27H44O3
MW:416.64
EINECS:658-064-6
Product Categories:Vitamin D3 analogs;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals

Paricalcitol Chemical Properties
 
Fp 14ºC
Form Neat
InChIKeyBPKAHTKRCLCHEA-UBFJEZKGSA-N
Quality StandardUSP41
 
Paricalcitol Usage

1) Synthetic analog of vitamin D. Antihyperparathyroid.

2) Antihyperparathyriod

3) 1,25-Dihydroxy vitamin D2 is a potent agonist of the vitamin D receptor. Paricalcitol is a synthetic 1,25-dihydroxy vitamin D2 analog. As vitamin D deficiency, associated with chronic kidney disease, leads to an increase in parathyroid hormone (secondary hyperparathyroidism), paricalcitol is used in renal patients to block parathyroid hormone overproduction. Vitamin D deficiency is also a risk factor in cancer, cardiovascular disease, hypertension, and diabetes, and paricalcitol may have applications in those contexts as well.

Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1
Function

It is used for the prevention and treatment of SHPT, and the prevention and treatment of SHPT in patients with stage III and IV chronic kidney disease (CKD) before dialysis and transplantation.

 

Packing & Shipment
 
Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1


Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process. 
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis. 
3) Procurement-Strictly on selecting raw materials. 
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards. 
5) Warehousing and storage: Clear and dry condition with suitable temperature. 
6) Transportation - Audit and supervise the logistics environment to ensure storage safety. 
7) Keep samples for all batches goods to be traceable in case of quality discrepance. 
Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1

Certification 

Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1

Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1

Reasonable Price Vitamin D Derivative Anti-Cancer API Paricalcitol Powder in Stock CAS 131918-61-1
 
Q1: Which kind of payment terms do you accept? 
For small order, you can pay by T/T or Western Union, nomal order by T/T to our company account. 

Q2: Can you give me a discount price? 
Surely, It depend on your quantity. 

Q3: How can I get a sample? 
Free samples is available, but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders? 
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. 

Q5: How do you treat quality complaint? 
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your
M. P. 
  

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