Vancomycin hydrochloride is a narrow-spectrum antibiotic, which is only effective against Gram-positive bacteria, such as hemolytic streptococcus, pneumococcus, and enterococcus. It is particularly sensitive to drug-resistant Staphylococcus aureus. Its mechanism of action is to inhibit the synthesis of bacterial cell wall, which is mainly combined with the bacterial cell wall, so that certain amino acids cannot enter the glycopeptide of the cell wall.
 

Treatment of serious infections caused by susceptible organisms resistant to penicillins (Methicillin-resistant Staphylococcus aureus(MRSA) and multiresistant Staphylococcus epidermidis (MRSE)) or in individuals with serious allergy to penicillins.

Treatment of pseudomembranous colitis caused by Clostridium difficile; in particular, in cases of relapse or where the infection is unresponsive to metronidazole treatment (for this indication, vancomycin is given orally, rather than by its typical intravenous (IV) route).

For treatment of infections caused by gram-positive microorganisms in patients with serious allergies to beta-lactam antimicrobials.

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