Monobenzone is an organic chemical in the phenol family with chemical formula C13H12O2

It is used as a topical drug for medical depigmentation.It is a colourless solid that is classified as the monobenzyl ether of hydroquinone. Monobenzone is soluble in alcohol, benzene, and diethyl ether, and practically insoluble in water.

Monobenzone can decompose melanin in the skin, and prevent the formation of melanin in the skin, used for the treatment of hyperpigmentation, such as various spots, age spots, melanoma. In addition as intermediates in organic synthesis.
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1.Monobenzone Powder is a compound used as a topical drug for medical depigmentation.
2.The topical application of monobenzone powder in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.
3.Monobenzone Powder may cause destruction of melanocytes and permanent depigmentation.
4.The histology of the skin after depigmentation with topical monobenzone powder is the same as that seen in vitiligo.
5.The epidermis is normal except for the absence of identifiable melanocytes.
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