99% J147 CAS 1146963-51-0 Nootropic Powder J 147

Product name: J147
Synonyms: J-147; J 147
CAS: 1146963-51-0
MF: C18H17F3N2O2
MW: 350.33
J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.
J-147 NSI-189 Coluracetam Sunifiram DM-235 Noopept

The approach that lead to development of the J147 drug was to screen candidate molecules for anti-aging effects, instead of targeting the amyloid plaques. It is contrary to most other approaches to developing drugs against Alzheimer's disease that target the plaque deposits in the brain.

The J147 drug is also reported to address other biological aging factors, such as preventing the leakage of blood from microvessels in mice brains. The development of J147 follows the chemical pharmacological way, contrary to biological ways that exploit e.g. use of bacteriophages.

Enhanced neurogenic activity over J147 in human neural precursor cells has its derivative called CAD-31. CAD-31 is enhancing the use of free fatty acids for energy production by shifting of the metabolic profile of fatty acids toward the production of ketone bodies, a potent source of energy in the brain when glucose levels are low.


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