China 99% Purity Nootropics Powder Donepezil HCl, Find details about China 110119-84-1 Donepezil HCl, Donepezil HCl from 99% Purity Nootropics Powder Donepezil HCl
Product Name: Donepezil
CAS: 120014-06-4
MF: C24H29NO3
MW: 379.492
Purity: 99%
MP: 207ºC
BP: 527.9°C at 760 mmHg
FP: 273.1°C
Density: 1.141g/cm3
Grade: Pharmaceutical Grade
Appearance: White Powder
Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.
Function
Donepezil has been tested in other cognitive disorders including Lewy body dementia and vascular dementia, but it is not currently approved for these indications. Donepezil has been found to improve sleep apnea in Alzheimer's patients. Donepezil has also been studied in patients with Mild Cognitive Impairment, schizophrenia, attention deficit disorder, post-coronary bypass cognitive impairment, cognitive impairment associated with multiple sclerosis, CADASIL, and Down syndrome.