Product Name:Lidocaine hcl
MF: C14H23ClN2O
MW:270.8
CAS : 73-78-9
Assays: above 99%
Packaging: 25kg/drum
Appearance: White Crystalline Powder

Lidocaine hydrochloride is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine hydrochloride. Approximately 90% of Lidocaine hydrochloride administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.

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1. The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action.
 
2. Epinephrine vasoconstricts arteries, reducing bleeding and also delays the resorption of
 lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available
formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine
makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic
procedures.
 
3. Relative insensitivity to lidocaine is genetic. In hypokalemic sensory overstimulation, relative
insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity
disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons
due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.
 
4. Lidocaine, along with ethanol,  has also been proven to be effective in
 treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

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