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Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/ 501516 Low Price CAS 317318-70-0

China Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0, Find details about China 99% Purity, Chemical Materials from Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

Model NO.
317318-70-0
Appearance
White Powder
Molecular Formula
C21h18f3no3s2
Grade
Pharmaceutical Grade
Trademark
Wingroup
Transport Package
Drum / Aluminum Foil Bag
Origin
Wuhan, China
Model NO.
317318-70-0
Appearance
White Powder
Molecular Formula
C21h18f3no3s2
Grade
Pharmaceutical Grade
Trademark
Wingroup
Transport Package
Drum / Aluminum Foil Bag
Origin
Wuhan, China
 

Product Description

 

Product  NameGW-501516
Synonyms2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]aceticacid;GW-501516,>=98%;ENDUROBOL(GW-501516)/CARDARINE/;Cardarine(GW-501516,GSK-516);GW-501615;CB646Chemicalbook5728;2-(4-((2-(4-(Trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetica;{2-Methyl-4-[4-Methyl-2-(4-trifluoroMethyl-phenyl)-thiazol-5-ylMethylsulfanyl]-phenoxy}-aceticacid
CAS NO317318-70-0
Molecular FormulaC21H18F3NO3S2
Molecular Weight453.5
Melting point134-136°C
Boiling Point584.5±60.0 °C at 760 mmHg
Flash Point307.3±32.9 °C
Density1.4±0.1 g/cm3
Purity≥97%
GradePharmaceutical Grade
SolubilityDMSO: soluble20mg/mL, clear
Appearancewhite to beige powder
StorageStore at dry and cool place
Packing and ShippingPacking: Drum / Aluminum Foil  Bag / According to customer's requiement                                                      Shipping: 3-5 working days after receive payment, by  Fedex,UPS,EMS,DHL,Sea and air transport
UsageIt is the best in terms of  endurance, energy, endurance and any type of performance improvement

Description:

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

GW-501516 (also known as GW-501,516, GW-1516, GSK-516, Cardarine,  is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. It entered into clinical development as a drug candidate for metabolic and cardiovascular diseases.

Exercise can increase peroxisome proliferator-activated receptor-δ (PPARδ) expression in skeletal muscle. PPARδ regulates muscle metabolism and reprograms muscle fibre types to enhance running endurance. This study utilized metabolomic profiling to examine the effects of GW-501516, a PPARδ agonist, on running endurance in mice.

 

 

Reference:
 

1. Koh B (2013-03-22). "Anti-doping agency warns cheats on the health risks of Endurobol". The Conversation.

 

2. Sahebkar A, Chew GT, Watts GF (March 2014). "New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease". Expert Opinion on Pharmacotherapy. 15 (4): 493-503. doi:10.1517/14656566.2014.876992. PMID 24428677. S2CID 21158696. Despite these promising early results, the further investigation and development of GW-501516 was discontinued after observations in animal studies of its association with the rapid induction of cancers in several organs (liver, stomach, tongue, skin, bladder, ovaries, womb and testes

 

3. "GW-501516 GlaxoSmithKline, Ligand milestone payment". R & D Focus Drug News. 28 June 2004.

 

4. Wolf G (November 2003). "The function of the nuclear receptor peroxisome proliferator-activated receptor delta in energy homeostasis". Nutr. Rev. 61 (11): 387-90. doi:10.1301/nr.2003.nov.387-390. PMID 14677574. S2CID 12362203.

 

5. Oliver WR, Shenk JL, Snaith MR, Russell CS, Plunket KD, Bodkin NL, Lewis MC, Winegar DA, Sznaidman ML, Lambert MH, Xu HE, Sternbach DD, Kliewer SA, Hansen BC, Willson TM (April 2001). "A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport". Proc. Natl. Acad. Sci. U.S.A. 98 (9): 5306-11. Bibcode:2001PNAS...98.5306O. doi:10.1073/pnas.091021198. PMC 33205. PMID 11309497.

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

 

Detailed Photos

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

Company Profile

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

Our Advantages

Wuhan wingroup Chemicals customers have expanded to North America, Europe, India, and we are constantly exploring and working hard.

Companies adhering to the concept of scientific and technological innovation, green environmental protection, honest and trustworthy, and common development, dedicated to provide customers at home and abroad with reasonable prices, quality products and professional technical services.

Certifications

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

Packaging & Shipping

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post andother couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided andsent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders,we ensure that goods can be  delivered in multiple ways safetly and efficiently.

FAQ

Q1:Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2:Which kind of payment terms do you accept?
A: Payment by T/T, Western Union or Bitcoin.

Q3:Which transportation do we use?
A:Samples could be DHL, UPS, TNT, EMS, Fedex, and so on. For mass orders, it will be delivered by air or sea.

Q4:How about your delivery time?
A:Generally, it will take 3 to 5 days after receiving your advance payment.

Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6:How can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.

Q7:Do you test all your goods before delivery?
 A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.

Food Additive Raw Materials Save Shipping High Purity Research Chemical Gw/501516 Low Price CAS 317318-70-0

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