Basic Info.

Model NO.

YP178-2

Model NO.

YP178-2

Product Desciption

Item Name:nifedipine tablets
Molecular formula:C₁₇H₁₈N₂O₆

Item Description

Item nanme:nifedipine tablets
Item character:This product is sugar coated tablets. It turns yellow after removing the coating

Indication:
1. Angina pectoris: variant angina pectoris; Unstable angina pectoris; Chronic stable angina pectoris.
2. Hypertension (alone or combined with other antihypertensive drugs).

Item specifications: 10mg*100s/box

Usage and dosage:1. The dose of nifedipine should be gradually adjusted according to the patient's tolerance and control of angina pectoris. Overdose of nifedipine can lead to hypotension.
2. Starting from a small dose, the general starting dose is 10mg / time (one tablet at a time) and taken orally three times a day; The commonly used maintenance dose is 10-20mg / time (1-2 tablets per time), 3 times a day. Some patients with obvious coronary spasm can be used up to 20-30mg / time (2-3 tablets at a time), 3-4 times a day. The maximum dose should not exceed 120mg / day (12 tablets per day). If the condition is urgent, chew or sublingual 10mg / time (one tablet at a time) and decide to give it again according to the patient's response to the drug.
3. It usually takes 7-14 days to adjust the dose. If the patient's symptoms are obvious and the condition is urgent, the dose adjustment period can be shortened. According to the patient's response to the drug, the frequency of attack and the dose of sublingual nitroglycerin, the dosage of nifedipine can be adjusted from 10-20mg (1-2 tablets) to 30mg / time (3 tablets at a time), three times a day.
4. For hospitalized patients under strict monitoring, 10mg (1 tablet) can be added every 4-6 hours according to the control of angina pectoris or ischemic arrhythmia.

Adverse reactions
1. The dose of nifedipine should be gradually adjusted according to the patient's tolerance and control of angina pectoris. Overdose of nifedipine can lead to hypotension.
2. Starting from a small dose, the general starting dose is 10mg / time (one tablet at a time) and taken orally three times a day; The commonly used maintenance dose is 10-20mg / time (1-2 tablets per time), 3 times a day. Some patients with obvious coronary spasm can be used up to 20-30mg / time (2-3 tablets at a time), 3-4 times a day. The maximum dose should not exceed 120mg / day (12 tablets per day). If the condition is urgent, chew or sublingual 10mg / time (one tablet at a time) and decide to give it again according to the patient's response to the drug.
3. It usually takes 7-14 days to adjust the dose. If the patient's symptoms are obvious and the condition is urgent, the dose adjustment period can be shortened. According to the patient's response to the drug, the frequency of attack and the dose of sublingual nitroglycerin, the dosage of nifedipine can be adjusted from 10-20mg (1-2 tablets) to 30mg / time (3 tablets at a time), three times a day.
4. For hospitalized patients under strict monitoring, 10mg (1 tablet) can be added every 4-6 hours according to the control of angina pectoris or ischemic arrhythmia.

Taboo:
It is forbidden for those allergic to nifedipine.

Matters needing attention:
1. Most patients with hypotension have only mild hypotension reaction after taking nifedipine, and some patients have serious hypotension symptoms. This reaction often occurs during the dose adjustment period or dosage addition, especially in combination β- Receptor blockers. Blood pressure should be monitored during this period, especially when combined with other antihypertensive drugs.
2. Fentanyl anesthesia for patients undergoing coronary artery bypass grafting (or other operations), taking nifedipine alone or with β- The combination of receptor blockers can lead to severe hypotension. If conditions permit, the drug should be stopped for at least 36 hours.
3. Very few patients with angina pectoris and / or myocardial infarction, especially patients with severe coronary stenosis, have reflex sympathetic excitement and accelerated heart rate after hypotension, and the incidence of angina pectoris or myocardial infarction increases.
4. Peripheral edema 10% of patients had mild to moderate peripheral edema, which was related to arterial dilation. Edema mostly occurs at the end of lower limbs, which can be treated with diuretics. For patients with congestive heart failure, it is necessary to distinguish whether edema is caused by further deterioration of left ventricular function.
5. β- Receptor blocker "rebound" symptoms suddenly stopped β- Receptor blockers and nifedipine can be used, sometimes with angina pectoris. The dosage of the former must be gradually reduced.
6. Congestive heart failure is rarely accepted β- Patients with receptor blockers can develop heart failure after taking nifedipine, and patients with severe aortic stenosis are at greater risk.
7. Interference in diagnosis. When using this product, alkaline phosphatase, creatine phosphokinase, lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase may occasionally increase. Generally, there are no clinical symptoms, but cholestasis and jaundice have been reported; Platelet aggregation decreased and bleeding time prolonged; Direct Coomb test positive with / without hemolytic anemia
8. Liver and kidney dysfunction, taking β- Receptor blockers should be used with caution and should be started from a small dose to prevent inducing or aggravating hypotension and increasing the incidence of angina pectoris, heart failure and even myocardial infarction. Patients with chronic renal failure occasionally have reversible increases in blood urea nitrogen and creatinine, and the relationship with nifedipine is not clear.
9. Sudden stop is not suitable for long-term administration to avoid rebound due to withdrawal syndrome.

Medication for pregnant and lactating women:
1. There is no detailed clinical research data. Nifedipine is clinically used in pregnant women with hypertension.
2. Nifedipine can be secreted into breast milk. Lactating women should stop taking drugs or breast-feeding.

FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the  authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.




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