China CAS No.: 131-48-6 N-Acetylneuraminic Acid/Sialic Acid, Find details about China Nutrition Enhancers, Food Additive from CAS No.: 131-48-6 N-Acetylneuraminic Acid/Sialic Acid
N-Acetylneuraminic Acid, also konwn as Sialic Aicd, is a key component of important amino sugars that mediate cellular communication. Sialic acid is a naturally-occuring building block foe compounds such as glycoproteins and gangliosides.
N-acetylneuraminic acid(Neu5Ac, NAN, NANA) is manufactured up to large scale to customer order.
N-acetylneuraminic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a nine-carbon monosaccharide. It is also the name for the most common member of this group, N-acetylneuraminic acid (Neu5Ac or NANA) and this is the name used by CIMA.
Nacetylneuraminic acid are found widely distributed in animal tissues and in bacteria, especially in glycoproteins and gangliosides. The amino group bears either an acetyl or a glycolyl group.
N-acetylneuraminic acid is a synthetic product and is the pure N-acetyl compound.
Nacetylneuraminic acid is also found widely in endothelial tissue and elsewhere; conjugated to a range of glycoproteins and glycolipids. It is considered to be the functional part of sialyllactose found in milk and colostrum.
Despite its role of acting as "decoy" for invading pathogens, Neu5Ac is becoming known as an agent necessary for mediating ganglioside distribution and structures in the brain.Along with involvement in preventing infections (mucus associated with mucous membranes - mouth, nose, GI, respiratory tract), Neu5Ac acts as a receptorfor influenza viruses to allow attachment to mucous cells (an early step in contracting the flu).
In food and supplement
-Sialic acid is the predominant component found in the brain ,it is proved to be the key material in memory and learning function.
-Sialic acid is one of the nutritional component of human milk, it improves brain development of infants.
-As one of the eight essential glyconutrients for huamn body, it widely exists in the cell membrane and neuron. It can enhance the body immunity.
In cosmetic
-Anti-aging: Sialic acid is a natural MMP-1 inhibitor. By reducing the expression of MMP-1 and its activity. Sialic acid could enable the aged disease cells back to normal status, and maintain the cell stability, greatly reduce the speed of cekk recession. And prolong the lifespan of skin cells so as ti achieve the effect of anti-aging. Therefore, long-term using skincare products containong sialic acid could effectively delay skin aging and promote skin regeneration.
-Whitening:Sialic acid can effectively inhibit tyrosine hydroxylase and dopa hudroxylase activity, preventing melanin basically.
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