China Manufacturers CAS 314728-85-3 Sunifiram Nootropic 99% Sunifiram Powder, Find details about China Sunifiram, Sunifiram Capsuls from Manufacturers CAS 314728-85-3 Sunifiram Nootropic 99% Sunifiram Powder
Manufacturers CAS 314728-85-3 Sunifiram Nootropic 99% Sunifiram Powder | |
Product Name: | Sunifiram |
Synonyms: | Piperazin, 1-benzoyl-4-(1-oxopropyl)-;SunifiraM;1-(4-Benzoyl-1-piperazinyl)-1-propanone;1-Benzoyl-4-(1-oxopropyl)-piperazin;1-(4-Benzoylpiperazin-1-yl)propan-1-one;1-Benzoyl-4 propanoylpiperazine;Sunifiram DM235 |
CAS: | 314728-85-3 |
MF: | C14H18N2O2 |
MW: | 246.30492 |
Mol File: | 314728-85-3.mol |
What is Sunifiram?
Sunifiram is a research ampakine that is becoming very popular amongst researchers. Sunifiram (DM-235) is a piperazin derived ampakine drug which acts as a positive allosteric
modulator of AMPA receptors, and has nootropic effects in animal studies with significantly
higher potency thanpiracetam. A number of related compounds are known, the best known
being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycinebinding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
Sunifiram DM235 is a research ampakine that is becoming very popular amongst researchers. As an ampakine, it works to improve the ability of the AMPA glutamate receptors. Sunifiram works by stimulating the AMPA receptor currents therefore improving the glutamate signal. This is believed to be the main method of action however there are several other applications of this compound.
1) Sunifiram is good at improved decision making.
2) Sunifiram greater ability to convert short-term memory into long-term memory.
3) Sunifiram Improved motor skills via increased control over muscle contraction.
4) Sunifiram can enhanced memory and retention of learned information and activities.
Items | Requirements | Results |
Appearance | White to off-white crystall powder | Conforms |
Loss on drying | ≤1.0% | 0.08% |
Mp | 93~97°C | 94.5~95.5°C |
Purity | ≥99.5 | 99.8% |
Solvent residue | ≤0.3% | 0.05% |
Conclusion | The product conforms to in House Standard | |
Packing and Storage | ||
Packing | Pack in two layers plastic-bag. | |
Storage | Store in a well-closed place with constant low temperature and no direct sun light. | |
Shelf life | 2 years when properly stored. |