Product Name: Gliclazide
CAS: 21187-98-4
MF: C15H21N3O3S
MW: 323.41
EINECS: 244-260-5
Melting point: 163-169 °C(lit.)
Storage temp.: -20°C Freezer

Gliclazide is an oral antihyperglycemic agent used for the treatment of diabetes mellitus type II. It belongs to the sulfonylurea class of secretagogues, which stimulates β cells of the pancreas to release. Gliclazide binds to the β cell sulfonyl urea receptor (SUR1), further blocking the ATP sensitive potassium channels. Therefore, the potassium efflux substantially decreases, causing depolarization of the β cells. Then the voltage-dependent calcium channels in the β cell are open, resulting in calmodulin activation, which in turn leads to exocytosis of containing secretorty granules. Recent studies have also shown that gliclazide can effectiveimprove anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes and protect pancreatic beta-cells from damage.

1. Fall blood sugar medicine, used in the treatment of non insulin dependent diabetes
2. It is mainly used for adult onset diet alone invalid, and no diabetes ketosis tendency of light duty.
3. Also improve diabetics fundus diseases and metabolic disorder of blood vessel function.

SINOBIO cooperate with different shipping company to help customer arrange the shipping for different quantity.

SINOBIO also can help to arrange the the DDP shipping to America and EUROPE which means we will let forwarder in charge of delivery and clear the customs, customer don't need to clear the customs and pay for additional customs cost by themselves.

Dalian Sinobio Chemistry Co.,Ltd was established in 2011 and located in beautiful costal city Dailan Liaoning Province. we can enjoy convenient transportation by all logistic ways . The key funders have more than 16 years experience on the chemical indudstry. The mainstream products include Biocides, pharmaceutical and functional chemicals. Such as carbomer940, Ethyl alcohol, PHMB20% ,SLES70%,BKC 50%/80%,ZPT, IPBC, Glutaraldehyde 50%, Sitagliptin and so on. During the pass 10 years, we gained a bunch of loyalty customers due to high quality products and the best services, and we have cooperated with multi-national company such as DOW,LANXESS, THOR etc. for more than 10years

Dalian Sinobio Chemistry Co.,Ltd are making great efforts to develop new products to meet customers' requirements. Warmly welcome customers from at home and abroad to cooperate with us for common success.

Q1: Can I get samples?

 A:   Yes, we can supply free sample, you pay for the freight charge only.
 

Q2: How to pay?

A: PI will be sent firstly after our aligned products specification. Payment by Paypal , T/T, Western Union,LC, Alipay are ok
 

Q3: How is your MOQ?

A: Normally speaking, our MOQ is 1kg. But we can also accept less quantity such as 100g on the condition that sample charge is 100% paid.
 

Q4: How can you guarantee the quality of your products?

1. Our staff are all experienced in chemical products or related major background, they are well trained before quotation.

2. Free sample or pre- shipment sample are available for our new cooperation before you place commercial order. We are sure the same specification commercial products as sample to customers

3. Third Party Inspection like SGS can be arranged according to your requirement before shipping.

4. On-Spot QC in our APPROVED associated production bases with necessary certification like GMP, ISO etc.