Anti-Allergic Drugs CAS 79794-75-5 Desloratadine Powder
China Anti-Allergic Drugs CAS 79794-75-5 Desloratadine Powder, Find details about China Desloratadine, Desloratadine Powder from Anti-Allergic Drugs CAS 79794-75-5 Desloratadine Powder
Basic Info.
Model NO.
HNB-282
Trademark
HNB-Biotech
Transport Package
Aluminium Foil Bag, Cardboard Drum
Origin
Shaanxi, China
Model NO.
HNB-282
Trademark
HNB-Biotech
Transport Package
Aluminium Foil Bag, Cardboard Drum
Origin
Shaanxi, China
Product Desciption
Anti-Allergic Drugs CAS 79794-75-5 Desloratadine Powder
Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.Target: Histamine H1 ReceptorDesloratadine binds to the human H1 receptor with Ki value of 0.87 nM in displacing tritiated mepyramine. Desloratadine (100 nM to 10 μM) inhibits both IgE-mediated and non-IgE-mediated generation of the cytokines IL-4 and IL-13 by human basophils. Desloratadine (300 nM to 100 μM) inhibits both IgE and non-IgE-mediated histamine release from human peripheral blood basophils. Desloratadine (0.1 μM to 10 μM) is also shown to inhibit platelet-activating factor-induced eosinophil chemotaxis and TNF-α-induced eosinophil adhesion in eosinophils obtained from patients with allergic rhinitis or allergic asthma
| Product name | Desloratadine |
| Cas No. | 100643-71-8 |
| Molecular Formula | C19H19ClN2 |
| Appearance | White powder |
Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.Target: Histamine H1 ReceptorDesloratadine binds to the human H1 receptor with Ki value of 0.87 nM in displacing tritiated mepyramine. Desloratadine (100 nM to 10 μM) inhibits both IgE-mediated and non-IgE-mediated generation of the cytokines IL-4 and IL-13 by human basophils. Desloratadine (300 nM to 100 μM) inhibits both IgE and non-IgE-mediated histamine release from human peripheral blood basophils. Desloratadine (0.1 μM to 10 μM) is also shown to inhibit platelet-activating factor-induced eosinophil chemotaxis and TNF-α-induced eosinophil adhesion in eosinophils obtained from patients with allergic rhinitis or allergic asthma
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