Natural Cosmetic Grade CAS 68797-35-3 Licorice Extract Dipotassium Glycyrrhizinate
China Natural Cosmetic Grade CAS 68797-35-3 Licorice Extract Dipotassium Glycyrrhizinate, Find details about China Dipotassium Glycyrrhizinate, Licorice Extract from Natural Cosmetic Grade CAS 68797-35-3 Licorice Extract Dipotassium Glycyrrhizinate
Basic Info.
Model NO.
68797-35-3
Product Name
Dipotassium Glycyrrhizinate
CAS Number
68797-35-3
Inci Name
Dipotassium Glycyrrhizinate
Molecular Weight
899.12g/Mol
Molecular Formula
C42h60K2o16
Appearance
White or Yellowish Powder
Particle Size
98% Through 80 Mesh
Einecs
272-296-1
Shelf Life
2 Years
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
98%
Origin
China
Model NO.
68797-35-3
Product Name
Dipotassium Glycyrrhizinate
CAS Number
68797-35-3
Inci Name
Dipotassium Glycyrrhizinate
Molecular Weight
899.12g/Mol
Molecular Formula
C42h60K2o16
Appearance
White or Yellowish Powder
Particle Size
98% Through 80 Mesh
Einecs
272-296-1
Shelf Life
2 Years
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
98%
Origin
China
Product Desciption
1.Dipotassium Glycyrrhizinate Overview
Dipotassium Glycyrrhizinate is a derivative of glycyrrhizic acid. It belongs to the triterpenoid saponin compound. Dipotassium Glycyrrhizinate is extracted from licorice root. It contains hydrophilic groups and lipophilic groups; so it can reduce surface tension of aqueous solution, and has a strong foaming ability. As an anti-allergy, sunscreen, anti-freckle, whitening cosmetic functional additive, Dipotassium Glycyrrhizinate can effectively prevent skin inflammation; and it has sedative effect on inflammation caused by sunlight. It is widely used in cosmetics industry. Dipotassium Glycyrrhizinate adopts two detection methods: HPLC (70%) and UV (98%), which ensures the purity of cosmetic grade Dipotassium Glycyrrhizinate, and makes customers relieved, secure and unworried.
2. Dipotassium Glycyrrhizinate Source
Licorice (Scientific name: Glycyrrhiza uralensis Fisch) belongs to leguminosae herbaceous perennial. It is also a traditional Chinese herb plant. Licorice mainly grows in arid, semi-arid sandy soil, desert edge and loess hilly area. Most of wild licorice in China is distributed in Sinkiang, Inner Mongolia, Ningxia, Gansu, Shanxi, and other places. There are a large number of artificial cultivation licorice areas in Sinkiang, Gansu, Inner Mongolia and Ningxia provinces. Licorice contains a variety of effective chemical components, such as liquiritin, glycyrrhizic acid, glycyrrhetinic acid, licorice flavonoids, liquiritigenin, etc. These components are mainly found in licorice root and bark. So the thick roots of licorice are major medicinal source commonly. Licorice extract is mainly used in the pharmaceutical, health care and cosmetics industries.
6. Dipotassium Glycyrrhizinate Benefits
1.Whitening
1) Inhibits active oxygen formation: Dipotassium Glycyrrhizinate is a flavonoid compound with strong antioxidant activity. Experimental study uses superoxide dismutase SOD as a control group, and the result shows that Dipotassium Glycyrrhizinate can effectively inhibit the production of active oxyge. 2) Inhibits tyrosinase: The IC50 of tyrosinase of Dipotassium Glycyrrhizinate is very low compared to the commonly used whitening ingredient. Dipotassium Glycyrrhizinate is a well-recognized strong tyrosinase inhibitor; it is more effective than some commonly used whitening agents. 3) Inhibits melanin production: Test selects the back skin of guinea pigs under UVB irradiation. The result indicates that white coefficient of skin pretreated with 0.5% Dipotassium Glycyrrhizinate is higher than that of the control group's skin, and the effect is obvious. Thus Dipotassium Glycyrrhizinate has a significant inhibitory effect on melanin formation. It can be used to prevent skin pigmentation and melanin production after sun exposure.
2.Anti-inflammation
The result of mouse ear swelling test shows that toothpaste containing Dipotassium Glycyrrhizinate can significantly inhibit xylene-induced ear swelling of mouse. So it has a strong anti-inflammatory effect for acute inflammation. The in vitro anti-inflammatory experiment of Dipotassium Glycyrrhizinate suggests that in a certain concentration range, Dipotassium Glycyrrhizinate inhibits cells from secreting inflammatory mediator NO and inflammatory cytokine IL-6, when it acts on LPS to stimulate RAW264.7 cells. And its inhibition function depends on a certain dosage. Therefore, Dipotassium Glycyrrhizinate has obvious anti-inflammatory activity in vitro.
7. Dipotassium Glycyrrhizinate Application and Reference Dosage
Dipotassium Glycyrrhizinate can be added into all kinds of cosmetics, such as cream, toner, emulsion, essence, etc. It can neutralize or reduce toxic substances in cosmetics; also it can prevent allergic reactions to some cosmetics. Moreover, Dipotassium Glycyrrhizinatecan can be used in advanced hair care products and teeth care products (toothpaste and mouthwash).
Attention:
1.The recommended dosage of Dipotassium Glycyrrhizinate in toothpaste is 1%-0.5%;
2.Dipotassium Glycyrrhizinate is suitable for combination with alpha hydroxy acid, which can increases skin defense ability.
8. Dipotassium Glycyrrhizinate Reference Formula
Anti-allergic emulsion:
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Dipotassium Glycyrrhizinate is a derivative of glycyrrhizic acid. It belongs to the triterpenoid saponin compound. Dipotassium Glycyrrhizinate is extracted from licorice root. It contains hydrophilic groups and lipophilic groups; so it can reduce surface tension of aqueous solution, and has a strong foaming ability. As an anti-allergy, sunscreen, anti-freckle, whitening cosmetic functional additive, Dipotassium Glycyrrhizinate can effectively prevent skin inflammation; and it has sedative effect on inflammation caused by sunlight. It is widely used in cosmetics industry. Dipotassium Glycyrrhizinate adopts two detection methods: HPLC (70%) and UV (98%), which ensures the purity of cosmetic grade Dipotassium Glycyrrhizinate, and makes customers relieved, secure and unworried.
| Product Name | CAS Number | INCI Name | |
| Dipotassium Glycyrrhizinate | 68797-35-3 | Dipotassium Glycyrrhizinate | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 899.12g/mol | C42H60K2O16 |  | |
Licorice (Scientific name: Glycyrrhiza uralensis Fisch) belongs to leguminosae herbaceous perennial. It is also a traditional Chinese herb plant. Licorice mainly grows in arid, semi-arid sandy soil, desert edge and loess hilly area. Most of wild licorice in China is distributed in Sinkiang, Inner Mongolia, Ningxia, Gansu, Shanxi, and other places. There are a large number of artificial cultivation licorice areas in Sinkiang, Gansu, Inner Mongolia and Ningxia provinces. Licorice contains a variety of effective chemical components, such as liquiritin, glycyrrhizic acid, glycyrrhetinic acid, licorice flavonoids, liquiritigenin, etc. These components are mainly found in licorice root and bark. So the thick roots of licorice are major medicinal source commonly. Licorice extract is mainly used in the pharmaceutical, health care and cosmetics industries.
3.Dipotassium Glycyrrhizinate VS Glycyrrhizic Acid
| Dipotassium Glycyrrhizinate | Glycyrrhizic Acid | |
| Source | Potassium derivatives of glycyrrhizic acid | Licorice root |
| Appearance | White powder | White crystalline powder |
| Molecular Structure | ||
| Solubility | Easily soluble in water; soluble in dilute ethanol, glycerol, slightly soluble in anhydrous ethanol, ether. | Hard to be soluble in cold water; easily soluble in hot water; insoluble in grease; its hot water solution is gelatinous after cooling. |
| Application | Whitening cosmetics, teeth care and hair care products | Food additives (Sweeteners, flavorings, flavor enhancers) and pharmaceuticals industry |
4.Specifications
5. Dipotassium Glycyrrhizinate Manufacturer Process Flow Chart| Product Name | Specification | Color |
| Dipotassium Glycyrrhizinate | 98% UV | White powder |
6. Dipotassium Glycyrrhizinate Benefits1.Whitening
1) Inhibits active oxygen formation: Dipotassium Glycyrrhizinate is a flavonoid compound with strong antioxidant activity. Experimental study uses superoxide dismutase SOD as a control group, and the result shows that Dipotassium Glycyrrhizinate can effectively inhibit the production of active oxyge. 2) Inhibits tyrosinase: The IC50 of tyrosinase of Dipotassium Glycyrrhizinate is very low compared to the commonly used whitening ingredient. Dipotassium Glycyrrhizinate is a well-recognized strong tyrosinase inhibitor; it is more effective than some commonly used whitening agents. 3) Inhibits melanin production: Test selects the back skin of guinea pigs under UVB irradiation. The result indicates that white coefficient of skin pretreated with 0.5% Dipotassium Glycyrrhizinate is higher than that of the control group's skin, and the effect is obvious. Thus Dipotassium Glycyrrhizinate has a significant inhibitory effect on melanin formation. It can be used to prevent skin pigmentation and melanin production after sun exposure.
2.Anti-inflammation
The result of mouse ear swelling test shows that toothpaste containing Dipotassium Glycyrrhizinate can significantly inhibit xylene-induced ear swelling of mouse. So it has a strong anti-inflammatory effect for acute inflammation. The in vitro anti-inflammatory experiment of Dipotassium Glycyrrhizinate suggests that in a certain concentration range, Dipotassium Glycyrrhizinate inhibits cells from secreting inflammatory mediator NO and inflammatory cytokine IL-6, when it acts on LPS to stimulate RAW264.7 cells. And its inhibition function depends on a certain dosage. Therefore, Dipotassium Glycyrrhizinate has obvious anti-inflammatory activity in vitro.
7. Dipotassium Glycyrrhizinate Application and Reference Dosage
Dipotassium Glycyrrhizinate can be added into all kinds of cosmetics, such as cream, toner, emulsion, essence, etc. It can neutralize or reduce toxic substances in cosmetics; also it can prevent allergic reactions to some cosmetics. Moreover, Dipotassium Glycyrrhizinatecan can be used in advanced hair care products and teeth care products (toothpaste and mouthwash).
| Product | Reference Dosage |
| Dipotassium Glycyrrhizinate 98% UV | 0.5-1% |
1.The recommended dosage of Dipotassium Glycyrrhizinate in toothpaste is 1%-0.5%;
2.Dipotassium Glycyrrhizinate is suitable for combination with alpha hydroxy acid, which can increases skin defense ability.
8. Dipotassium Glycyrrhizinate Reference Formula
Anti-allergic emulsion:
| Ingredient | Content(%) | Ingredient | Content(%) |
| Carbopol | 0.1 | Cetyl stearol polyoxyethylene (2) ether | 1.2 |
| Tocopherol | 0.5 | Cetyl stearol polyoxyethylene (21) ether | 1.5 |
| Triglycerides caprylic | 3.0 | Ethylhexyl palmitate | 4.0 |
| Polydimethylsiloxane | 2.0 | Hydrogenated polyisobutene | 5.0 |
| Methylparaben | 0.2 | Dipotassium Glycyrrhizinate | 0.2 |
| Glycerol | 5.0 | Ophiopogonis japonicus P.E | 1.0 |
| Fucose | 3.0 | Opuntia streptacantha stem extract | 2.0 |
| Deionized water | Add to 100.0 | Triethanolamine | 0.1 |
| Azone | 1.0 | ||
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