Anti -Atf-4 Rabbit Polyclonal Primary Antibodies
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Anti -ATF-4 Rabbit Polyclonal Primary Antibodies
Product Information| Description | ATF-4 rabbit polyclonal |
| Protein full name | Cyclic AMP-dependent transcription factor ATF-4 |
Synonyms | cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4 |
| Immunogen | Recombinant protein corresponding to Mouse ATF-4 |
Isotype | IgG |
Purity | Affinity purification |
| Subcellular location | Cell membrane, Cytoplasm, Nucleus |
| Uniprot ID | P18848, Q06507, Q9ES19 |
Applications
| Applications | IHC | IF |
| Species | Human, Mouse, Rat | Human, Mouse, Rat |
| Dilution | 1: 1500-1: 3000 | 1: 1500-1: 3000 |
| Positive tissue | colon, liver, brain, small intestine, kidney | breast, liver, brain |
Background
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse colon using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse liver using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse small intestine using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using ATF-4 (GB111137) at dilution of 1: 1600 |
| Immunofluorescent analysis of paraffin-embedded human breast using ATF-4 (GB111137) at dilution of 1: 1500 |
Storage
Storage | Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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