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Ivermectin is approved by the FDA for the treatment of intestinal strongyloidosis and onchocerciasis, two diseases caused by parasites. In addition, some topical forms of ivermectin are approved for the treatment of external parasites such as head lice and skin diseases such as rosacea.
Some forms of animal ivermectin are approved to prevent heartworm disease and treat certain internal and external parasites.


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There is a group of clinicians in the United States called FLCCC that has conducted a meta-analysis of all published papers on ivermectin and found that the effect of using ivermectin in the early stages of infection is about 82%.