China Anti-Allergic Drugs Loratadine Powder CAS 79794-75-5 Loratadine, Find details about China Loratadine, Loratadine Raw Material from Anti-Allergic Drugs Loratadine Powder CAS 79794-75-5 Loratadine
The Leader Manufacturer of Powder-TGY Bioteach
Product | Loratadine/ Desloratadine |
CAS: | 79794-75-5 |
MF: | C22H23ClN2O2 |
MW: | 382.88 |
MP: | 134-136°C |
Storage temp: | 2-8°C |
Solubility DMSO: | 26 mg/mL, soluble |
Appearance: | white powder |
Purity: | 99%+ |
Loratadine is a medication used to treat allergies. This includes allergic rhinitis(hay fever) and hives. . It is taken by mouth.Common side effects include sleepiness, dry mouth, and headache.Serious side effects are rare and include allergic reactions,seizures, and liver problems.Use during pregnancy appears to be safe but has not been well studied. It is not recommended in children less than two years old.It is in the second-generation antihistamine family of medication.
Loratadine is indicated for the symptomatic relief of allergy such as hay fever (allergic rhinitis), urticaria (hives), chronic idiopathic urticaria,and other skin allergies.For allergic rhinitis (hay fever), loratadine is effective for both nasal and eye symptoms: sneezing, runny nose, itchy or burning eyes.
Loratadine Forms:
.Also available are quick-dissolving tablets, which are marketed as being faster to get into one's circulatory system, but require special handling to avoid degrading in the package.
Loratadine Dosage:
Adults and children over the age of 6 are typically given 10 mg of loratadine per day. This usually equates to two teaspoons or one tablet, but you should read the instructions on your package to make sure that this is the case for the brand you are working with. Children ages 2-5 should be limited to 5 mg or one teaspoon of the liquid form of loratadine per day. Children in this age group should not use loratadine tablets.
Pregnant women may be able to use loratadine without risk to their fetus, but there are no scientific studies that confirm whether or not this is a risk. Talk with your doctor about this risk before you start using loratadine to ensure that the benefits will outweigh the risks. If you are breastfeeding you may need to avoid using loratadine because it can be transferred to your child through the breast milk, and children are at an increased risk for side effects when exposed to loratadine.
Adults and children with liver failure or renal insufficiency may need to adjust their dosing to ensure that the drug is sufficiently clearing from your system before you take another dose. In most cases, this will mean taking the same sized dose recommended for your age group, but limiting your dosing to every other day. If you have any other concerns regarding how your doses should be administered, ask your doctor what kind of dosing schedule is appropriate for you.
Certification of Analysis
Product Name: | Loratadine | Formula Weight: | 382.89 |
Cas No: | 79794-75-5 | Odor: | odorless |
Formular: | C22H23ClN2O2 | Other name: | Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate |
TESTS | SPECIFICATIONS |
Description | Off white to white crystalline powder |
solubility parameter | n acetone, chloroform, methanol and toluene, soluble in water is almost insoluble. |
IdentifIcation | (1) Infrared absorption spectra should be consistent with those of the control products. |
(2) Retention time of the test items under the determination of the content should be consistent with that of the control product. | |
Loss on drying | ≤0.5% |
Residue on ignition | ≤0.1% |
Related Substances | Other unknown monohetero ≤0.5% Total impurities ≤1.0% |
Residual solvent | Isopropyl ether ≤0.5% |
Ethyl acetate≤0.5% | |
Toluene≤0.089% | |
Assay | C22H23ClN2O2 98.5%~101.0% |
Conclusion | Conform with specification |
Storage | Store in sealed containers at cool & dry place. |
| Protect from light, moisture and pest infestation. |
Shelf life | 2 years when properly stored |
Don't hesitate to contact us for latest COA
Xi'an Tian Guangyuan Biotech Co., Ltd.
Sophie Lee/Sales Manager
Tel: 86-29-86333380
Web:tgybio.en.made-in-china.com
XIAN Tian Guangyuan Biotech Co.,Ltd.Was founded in May 2003, is a professional animal and plant Extracts
modernand advanced enterprise object, chemical intermediates and active ingredients of Natural active
throughout the country,plant extracts industry, research and development, production,Marketing and other
areas have a strong strength.The company is headquartered in the outskirts of Xi'an, under research and
development center as well as analysisand testing center, comprehensive strength in the national forefront
of the industry.Companies rely on the wisdom andinnovation of advanced technology, scientific management
and all the staff and a good team spirit, will enable the companyto develop a domestic industry with sik-class
product quality and international competitiveness of enterprises.