China Sonwu Supply CAS 1613220-15-7 Anticancer Niraparib Tosylate Monohydrate, Find details about China Anticancer Niraparib Tosylate Monohydrate, Niraparib Tosylate Monohydrate from Sonwu Supply CAS 1613220-15-7 Anticancer Niraparib Tosylate Monohydrate
Name | Sonwu Supply CAS 1613220-15-7 Anticancer Niraparib Tosylate Monohydrate |
CAS NO. | 1613220-15-7 |
Molecular Formula | C26H28N4O4S |
MW | 492.59 |
Purity | 99% |
Appearanc | White powder |
Certificate | ISO, SGS, GMP, HACCP |
MOQ | 10 g |
Shelf life | 2 Years |
Nirapanib p-toluenesulfonate is a sulfonic acid organic compound, which can be used as a pharmaceutical intermediate. The chemical name of niraparib is 2-[4-((3S)-3-piperidinyl)phenyl]-2H-indazole-7-formyl, which is an oral poly ADP ribose polymer developed by Tesaro. Enzyme (PARP) inhibitors can inhibit cell repair of DNA damage, mainly for cancers with BRCA mutations, such as ovarian cancer and breast cancer.
Niraparib is an orally active small molecule PARP inhibitor developed by Tesaro to treat ovarian cancer.The drug is approved by the US FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy.
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