China High Purity 99% Agomelatine Powder CAS 138112-76-2, Find details about China Agomelatine, Agomelatine Powder from High Purity 99% Agomelatine Powder CAS 138112-76-2
Chemical name: Agomelatine
CAS registry number: 138112-76-2
Chemical Formula: C15-H17-N-O2
Molecular Weight: 243
Therapeutic Category: Antidepressant: Melatonin receptor agonist
Chemical Names: N-[2-(7-metoxy-1-naphtyl)etyl]acetamide (WHO),N-[2-(7-Metoxynaphtalen-1-yl)etyl]acetamide (BAN)
Appearance: White powder
Drug class: Atypical antidepressant drug
Agomelatine is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep.
Function
1.As a Pharmaceutical Intermediates, Agomelatine is used in the treatment of major depressive disorder, emotional disorder.
2.Agomelatine is used in the treatment of major depressive disorder, emotional disorder. The drug substance for Nervous system. Antidepressant, anxiolytic, adjusting the rhythm of sleep and regulating biological clock.
3.Agomelatine is a melatoninergic agonist and selective antagonist of 5-ht2c receptors.
4.Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
5.Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant.
Application
Agomelatine is indicated for the treatment of major depressive episodes in adults. Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short- term double-blind placebo-controlled studies. Two were considered "failed" trials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies. The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study.
Shandong Longilat Biotechnology Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales.
Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world.
1.Can I get some samples?
Yes, usually a 10-20g sample.
2.What's your MOQ?
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.
3. Is there a discount?
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.
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≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.
5. What is the shelf life for the products?
Most products shelf life 24-36 months.
6. What's your delivery time?
Usually, shipment will be made within 7-15 days against confirmed order.
7. How about the validity of the offer?
Usually, our offer is valid for 1 week. However, validity might vary between different products.