Factory Supply Diltiazem CAS 42399-41-7 Diltiazem in Stock
China Factory Supply Diltiazem CAS 42399-41-7 Diltiazem in Stock, Find details about China Diltiazem, Diltiazem Powder from Factory Supply Diltiazem CAS 42399-41-7 Diltiazem in Stock
| Product Name | Diltiazem |
| Appearance | white powder |
| Name | Diltiazem powder |
| Purity | 99%min |
| Grade | Phamaceutical Grade |
| CAS | 42399-41-7 |
| COA | available |
| Shelf life | 2 Years |
Diltiazem is indicated for:
Stable angina (exercise-induced) - diltiazem increases coronary blood flow and decreases myocardial oxygen consumption, secondary
to decreased peripheral resistance, heart rate, and contractility.
Variant angina - it is effective owing to its direct effects on coronary dilation.
Unstable angina (preinfarction, crescendo) - diltiazem may be particularly effective if the underlying mechanism is vasospasm.
Diltiazem Function:
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.Chemically, it is based upon a 1,4-thiazepine ring, making it a benzothiazepine-type calcium channel blocker.
It is a vasodilator of coronary and peripheral vessels, which reduces peripheral resistance and afterload, though not as potent as the dihydropyridine (DHP) calcium channel blockers. This results in minimal reflexive sympathetic changes.
Diltiazem has negative inotropic, chronotropic, and dromotropic effects. This means diltiazem causes a decrease in heart muscle contractility - how strong the beat is, lowering of heart rate - due to slowing of the sinoatrial node, and a slowing of conduction through the atrioventricular node - increasing the time needed for each beat. Each of these effects results in reduced oxygen consumption by the heart, reducing angina symptoms. These effects also reduce blood pressure by causing less blood to be pumped out.
Diltiazem Picture show:
Diltiazem COA:
Items |
Specification |
Result |
Assay | 98.5%-101.5% | 99.48% |
Appearance | White crystalline powder | Conform |
Specific rotation | +110°~+116° | +115° |
Loss on drying | ≤0.5% | 0.21% |
Residue on ignition | ≤0.1% | 0.02% |
Heavy metals | ≤20ppm | <20ppm |
Related compounds | Total impurities≤1.0% Other single impurity≤0.5% | 0.42% 0.16% |
Packing &Shipping:
Liquid:
Iron drum & plastic drum packaging
25kg /drum
170kg per unit
IBC/ISO tank
Solid
Plastic bag & kraft paper bag & fiber drum
1kg per bag
25kg per bag/drum
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Company profile:
Hebei Guanglang Biotechnology Co,.LTD is a fast growing intermediates company,Which located in Shijiazhuang, Hebei Province.
Hebei Guanglang Biotechnology Co,.LTD is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., Crovell also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,Hebei Guanglang Biotechnology Co,.LTD has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
Warehouse stock:
Our advantage:
Our team:
Certificate:
Exhibition:
Payment term:
FAQ:
Q: How to start orders or make payments?
A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and
we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the
samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q: What's your MOQ?
A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts
from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantity, we always support with better price.
Q:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we
will send you free goods for replacement or refund your loss.
Q:How to contact us ?
You can choose your interested products and send inquiry to us.You can dial our telephone directly, you will get our reply.
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