Name: 2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, N-[3-(Aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-5-methyl-3-(trifluoromethyl)-1H-pyrazole-1-acetamide,
2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS: 489408-02-8
Systematic Name: YDL223C
Molecular Structure: C16H17F3N4O2S
Molecular Weight: 386.39
Assay: 99.0%min(HPLC)

HBT1 is a novel potent AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator with lower agonistic effect compared with LY451395 and OXP1, it induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.

 

Application&Function

1. Yeast genomic knockout strain
2. Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby
implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication
3. Applied in pharmaceutical field.

Chemical Properties 

Exact Mass	386.1024
Solubility	DMSO: 2 mg/mL, clear
InChI Key	PHLXSNIEQIKENK-UHFFFAOYSA-N
Smiles	O=C(C1=C(NC(CN2N=C(C(F)(F)F)C=C2C)=O)SC3=C1CCCC3)N
Moisture	0.5%Max
Physical state	Powder
Application	Intermediate in organic syntheses
Production Scale	Up to kgs

Package & Delivery

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Payment

Our services

1. All inquiries will be replied within 12 hours. 

2. Dedication to quality, supply & service. 

3. Strictly on selecting raw materials. 

3. OEM/ODM Available. 

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development. 

6. Faster delivery:Sample order in stock and 3-7 days for bulk production. 

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder. 

8. After-Sale Service: 

1) International Authorized Third-Party Test For The Products You Demand. 

2) 30 Days Warranty of quality of goods.

About us

FAQ

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Our MOQ is 10pcs.

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Q9.Can I get the sample?
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Q10.Can you accept customized?
Yes,we can according your require to do it.

Q11.How do I place the order?
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