Pharmaceutical Manufacturing Heavy Metal Antidote Dmsa Dimercaptosuccinic Acid
China Pharmaceutical Manufacturing Heavy Metal Antidote Dmsa Dimercaptosuccinic Acid, Find details about China Dmsa Dimercaptosuccinic Acid, Dmsa Powder from Pharmaceutical Manufacturing Heavy Metal Antidote Dmsa Dimercaptosuccinic Acid
Basic Info.
Model NO.
JULONG-DMSA
Product Name
Dmsa
Shelf Life
2 Years
MOQ
1kg
Application
Pharmaceutical Raw Intermediates
Test Method
HPLC
Main Ingredient
Dmsa
Grade Standard
Medicine Grade
Appearance
White Powder
Delivery Time
3-7days
Packaging
1kg 25kg
Storage Conditions
Cool Dried Storage
Keyword
Dmsa
Certificate
ISO, Halal, Kosher
Type
Anesthetic Agents
Trademark
JULONG
Transport Package
1kg/ Foil Bag
Specification
99%
Origin
China
HS Code
2934999000
Model NO.
JULONG-DMSA
Product Name
Dmsa
Shelf Life
2 Years
MOQ
1kg
Application
Pharmaceutical Raw Intermediates
Test Method
HPLC
Main Ingredient
Dmsa
Grade Standard
Medicine Grade
Appearance
White Powder
Delivery Time
3-7days
Packaging
1kg 25kg
Storage Conditions
Cool Dried Storage
Keyword
Dmsa
Certificate
ISO, Halal, Kosher
Type
Anesthetic Agents
Trademark
JULONG
Transport Package
1kg/ Foil Bag
Specification
99%
Origin
China
HS Code
2934999000
Product Desciption
Product Name | DMSA Powder |
CAS No. | 304-55-2 |
Other name: | dimercaptosuccinic acid |
Appearance | White Crystalline Powder |
Assay | 99% |
Solubility: | which is soluble in alkaline solution, slightly soluble in methanol and insoluble in water. |
DMSA is the organosulfur compound with the formula HO2CCH(SH)CH(SH)CO2H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour. It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as achelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water soluble and non-toxic substance.
FUNCTION:
DMSA is a chelator that is able to bind to metals in the body which can then be expelled through the urine. It will reduce levels of toxic metals like lead and arsenic but also essential metals like copper and zinc. Supplements are usually prescribed with DMSA to ensure levels of essential metals are not diminished along with toxic ones. DMSA capsules can be compounded in multiple strengths to meet each individual patient's needs.
APPLICATION:
DMSA Powder is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments.Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often
used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.
used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.
The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound DMSA.
By Express | By Air | By Sea | ||
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods | Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed | Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed | ||
Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
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