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99% Purity CAS 366789 -02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban

China 99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban, Find details about China Rivaroxaban, Material Rivaroxaban from 99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban

Model NO.
D-sung Rivaroxaban
Product Name
Rivaroxaban
Name
Rivaroxaban Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Antithrombotic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
366789-02-8
Mf
C19h18cln3o5s
MW
435.88132
Density
1.46
Boiling Point
732.6°cat760mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Rivaroxaban
Product Name
Rivaroxaban
Name
Rivaroxaban Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Antithrombotic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
366789-02-8
Mf
C19h18cln3o5s
MW
435.88132
Density
1.46
Boiling Point
732.6°cat760mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
Product Description
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
Product Details
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
Product nameRivaroxaban
Cas number366789-02-8
ApperanceWhite powder
MFC19H18ClN3O5S
MW435.88132
Density1.46
Boiling point732.6°Cat760mmHg
Venous thromboembolism continues to be a major health concern despite conventional anticoagulation therapies. Rivaroxaban is a recent market introduction that directly inhibits FXa with high potency (Ki=0.4 nM; IC50=0.7 nM) and selectivity>10,000-fold over other related serine (thrombin, trypsin, plasmin, FVIIa, FIXa, FXIa, urokinase, and activated protein C). From the X-ray crystal structure, the central oxazolidinone moiety anchors the drug through two hydrogen bonds to Gly219 and directs the morpholinone group into the S4 pocket and the chlorothiophene portion into the S1 pocket. These key components may be coupled together synthetically by a couple of routes. Condensation of 3-morpholinone with 4-fluoronitrobenzene followed by catalytic hydrogenation provides N-(p-aminophenyl)morpholinone for subsequent reaction with (S)-2-(phthalimidomethyl)oxirane. With establishment of the aminoalcohol adduct, cyclization with 1,1′-carbonyldiimidazole generates the central oxazolidinone. Deprotection and acylation with 5-chlorothiophene-2-carbonyl chloride affords rivaroxaban.
Application&Function
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic RivaroxabanRivaroxaban is recommended as an option for treating pulmonary embolism and preventing recurrent deep vein thrombosis and pulmonary embolism in adults.
1. Rivaroxaban (Xarelto, Bayer) is indicated for the 'treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults'. For the initial treatment of acute pulmonary embolism, the recommended dosage of rivaroxaban is 15 mg twice daily for the first 21 days followed by 20 mg once daily for continued treatment and prevention of recurrent venous thromboembolism.
2. Non-Valvular Atrial Fibrillation (NVAF)* to prevent stroke & systemic embolism.
3. Acute VTE treatment & prevention of recurrent VTE [for deep vein thrombosis (DVT) and pulmonary embolism (PE)].
4. Prevention of venous thromboembolic events (VTE) in elective total hip or knee replacement surgery (THR, TKR).
Specification
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban
99% Purity CAS 366789-02-8 Rivaroxaban Material Rivaroxaban Powder Rivaroxaban Antibiotic Rivaroxaban

 
 

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