Raw Material Domperidone Powder for Antiemetic CAS 57808 -66-9

China Raw Material Domperidone Powder for Antiemetic CAS 57808-66-9, Find details about China Antiemetic, Domperidone from Raw Material Domperidone Powder for Antiemetic CAS 57808-66-9

Model NO.
CAS 57808-66-9
Appearance
White Powder
Delivery Time
7-10 Days
Trademark
Biocar
Transport Package
Foil Bag and Drum
Specification
1kg/bag or 25kgs/drum
Origin
China
Model NO.
CAS 57808-66-9
Appearance
White Powder
Delivery Time
7-10 Days
Trademark
Biocar
Transport Package
Foil Bag and Drum
Specification
1kg/bag or 25kgs/drum
Origin
China
Raw Material Domperidone Powder for Antiemetic CAS 57808-66-9 

Detail

Domperidone
CAS No.:57808-66-9
Synonyms:6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one;
Formula:C22H24ClN5O2
Exact Mass:425.16200
Molecular Weight:425.91100
PSA:78.82000
LogP:3.29110
Appearancewhite powder
Density:1.341 g/cm3
Melting Point:242.5ºC
Stability:Stable. Incompatible with strong oxidizing agents.
Storage Condition:Keep tightly closed.

 
 

Raw Material Domperidone Powder for Antiemetic CAS 57808-66-9



Description

  1. A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.
  2. Domperidone is a commonly used antiemetic and gastro-kinetic drug with its appearance being white to light yellow powder and bitter taste. It is almost insoluble in water, slightly soluble in ethanol, easily soluble in lactic acid as well as soluble in citrate. This product is a kind of peripheral dopamine receptor antagonists with strong action.
  3. Domperidone can block the DA1 and DA2 receptor next to the synapses, antagonizing the inhibitory effect of dopamine on the postsynaptic cholinergic neurons of myenteric plexus and causing the stomach contractions. It can promote the motility and tension of digestive tract motility to return to normal function, promoting the emptying of stomach, increasing the motility of gastric antral and duodenum, coordinating the contraction of the pylorus as well as enhancing the esophageal peristalsis and the tension of the lower esophageal sphincter.

Application

1). Domperidone is a kind of phenyl compounds with a strong role in promoting gastric motility and antiemetic effect. It can strengthen the tension of the sphincter of the lower part of the esophagus, preventing the stomach - esophageal reflux, enhancing the gastric motility, promoting the gastric emptying, coordinating the stomach and duodenal motility, suppressing nausea, vomiting, and effectively preventing the bile reflux without affecting the secretion of gastric juice.

2). This product is a kind of peripheral dopamine receptor antagonists which can directly block the gastrointestinal dopamine receptors and exhibit the stimulating effect of gastric motility. It can enhance the esophageal peristalsis and the tension of esophageal sphincter. Because of its poor penetration through the blood brain barrier, it has almost no antagonism against the dopamine receptor of the brain, and therefore can excluding the side effects of the spirit and the central nervous system.

Raw Material Domperidone Powder for Antiemetic CAS 57808-66-9


Our Advantage:

1.We have stock so we can delivery quickly at the very day when receive the payment.

2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.

3.High quality guarenteed, once any problem is found, the package would be reshipped for you

4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.

5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.


Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express


FAQ

1.How about parcel delivery success rate ?

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?

Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.

3.Do You Ship Over The Weekend?

We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.