Closantel is a broad-spectrum insect repellent, which has good effect on the larva of various kinds of nematode and arthropods. Its anti - absorption insect repellent activity is mainly aimed at the liver - schistosomiasis, and killing larvae of nematodes and arthropods are mainly targeted at various types of insects that use blood or plasma.Closantel is a kind of strong oxidative dissolving the coupling agent, which can inhibit phosphorylation process of mitochondria, so as to prevent insect body adenosine triphosphate (ATP) synthesis, leading to an insect physical metabolism vigor decrease rapidly and finally to death.