Raw Material Domperidon/Domperidone CAS 57808 -66-9

China Raw Material Domperidon/Domperidone CAS 57808-66-9, Find details about China Purity Domperidone, Material Domperidone from Raw Material Domperidon/Domperidone CAS 57808-66-9

Trademark
TZ
Transport Package
1kg/Bag 25kg/Drum
Specification
98%
Origin
China
Trademark
TZ
Transport Package
1kg/Bag 25kg/Drum
Specification
98%
Origin
China
Raw Material Domperidon/Domperidone CAS 57808-66-9 

Raw Material Domperidon/Domperidone CAS 57808-66-9Raw Material Domperidon/Domperidone CAS 57808-66-9

ProName: Domperidone
CasNo: 57808-66-9
Molecular Formula: C22H24ClN5O2
Appearance: White powder
Application: Pharmaceutical Intermediate
DeliveryTime: With about 7-10 days after receipt 
PackAge: as you requested
Port: China main port
ProductionCapacity: 100 Gram/Day
Purity: 99%
Storage: room temperature
Transportation: by courier, by sea
LimitNum: 1 Kilogram
Grade: Industrial Grade,Pharma Grade
Transportation: by courier

Product Name
Domperidone
Appearance
white powder
CAS No
57808-66-9
Delivery time
2-3 days
Loss on Drying
≤1.0%
packing
1kg/bag
Storage
Dry and cool place and keep away from strong light
Payment
BTC,TT,WU,MG
Customs
Free of customs
Sample
avaiable
Shelf life
2 years
Raw Material Domperidon/Domperidone CAS 57808-66-9
Raw Material Domperidon/Domperidone CAS 57808-66-9
 

Domperidone is a dopamine blocker and an antidopaminergic reagent.Target: Dopamine ReceptorDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets [1]. Domperidone is a dopamine D(2) receptor antagonist, which has been used as antiemetic agent in human beings. The percentage recovery of domperidone from wastewater was 95.0%. Cel iprolol was used as the internal standard to access the percentage extraction of domperidone from wastewater [2]. Domperidone, a dopamine antagonist that does not easily cross the blood-brain barrier, is considered the gold standard for treating gastrointestinal symptoms in patients with Parkinson's disease (PD) because the risk of developing extrapyramidal adverse effects is considered minimal.

Domperidone is a benzimidazole compound that has strong stomach-stimulating and antiemetic effects, can strengthen the lower esophageal sphincter tension, prevent gastric-esophageal reflux, enhance gastric motility, promote gastric emptying, and coordinate the stomach with the twelve-finger Intestinal exercise, inhibition of nausea, vomiting, and effective prevention of bile reflux, does not affect the secretion of gastric juice.

Raw Material Domperidon/Domperidone CAS 57808-66-9

Product name
Domperidone
Cas number
57808-66-9
EINECS No.
260-968-7
Items
Requirements
Results
Appearance
White to off white powder
White powder
Solubility
Practically insoluble in water, soluble in dimethylformamide,
slightly soluble in et hanol(96%) and in m ethanol
Confirms
Identification
A. M.P. 244~248ºC
244.5~245.5ºC
 
B. IR should comply
Confirms
 
C. TLC should comply
Confirms
 
D. It gives the reaction of non-nitrogen substituted barbiturates.
Confirms
Clarity of solution
The solution is clear and not more intensely colored than
reference solution Y6
Confirms
Related substance
Total impurities≤0.5%
≤0.29%
 
Individual impurity≤0.25%
≤0.18%
Loss on drying
≤0.5%
0.07%
Sulphated ash
≤0.1%
≤0.05%
Heavy metal
≤20ppm
<20ppm
Assay
99.0%~101.0%
99.49%
Raw Material Domperidon/Domperidone CAS 57808-66-9

1.Domperidone is used for the treatment of gastroparesis (especially diabetic gastro-light gastroparesis), which can eliminate the symptoms of gastric retention and shorten the gastric emptying time; patients with moderate to moderate functional dyspepsia (FD) It can completely eliminate or significantly reduce symptoms such as abdominal distention, epigastric pain, belching, early satiety, nausea, and vomiting after meals.

2.Domperidone has a significant effect on reflux gastritis, but it is not very satisfactory for the efficacy of reflux esophagitis.

3.Domperidone can be used as an adjunctive treatment for peptic ulcers (mainly gastric ulcers) to eliminate antral retention.

 

Nausea and vomiting .There is some evidence that domperidone powder has antiemetic activity.

Domperidone powder may be useful in diabetic and idiopathic gastroparesis.

Domperidone can be used to relieve gastrointestinal symptoms in Parkinson's disease,

Domperidone may be used in functional dyspepsia in both adults and children.

Raw Material Domperidon/Domperidone CAS 57808-66-9
Raw Material Domperidon/Domperidone CAS 57808-66-9


Raw Material Domperidon/Domperidone CAS 57808-66-9Raw Material Domperidon/Domperidone CAS 57808-66-9
Delivery Time: Around 3-10 workdays after your payment.
Package: 1kg/aluminum foil bag; 25kgs in fiber-drums with two plastic bags inside.
Net Weight: 25kgs/Drum Gross Weight:28kgs/Drum
Drum Size & Volume: I.D.42cm × H52cm,0.08 m³/Drum
Storage: Stored in a dry and cool place. Keep away from strong light and heat.
Shelf Life: Two years when properly stored.
Recommended transportation selections
By Express
By Air Transportation
By Sea Transportation
Suitable for sample order or quantities<50kg
Fast: 3-10 days
High shipping cost
Door to door service
Suitable for quantities>50kg
Fast: 3-7 days
Lower than express cost
Airport to airport service
Professional broker needed
Suitable for quantities> 300kg
Slow: 7-45 days
Lowest cost
Port to port service
Professional broker needed
Raw Material Domperidon/Domperidone CAS 57808-66-9