Closamide is a broad-spectrum anthelmintic, which has a good effect on a variety of trematodes, nematodes and arthropod larvae; its anti-fluke repellent activity is mainly against Fasciola hepatica, anti-nematodes and anti-nematodes. The repellent activity of arthropod larvae is mainly aimed at all kinds of worms that suck blood or plasma. This product is widely used in various infections of the above-mentioned parasitic diseases in cattle and sheep. It can be administered orally or parenterally (subcutaneously and intramuscularly), and it has both therapeutic and preventive effects. There are injections, pills and soaking agents on the market. Generally, it is compatible with mebendazole and other benzimidazole products to make compound soaking agent for sheep body; it is compatible with levamisole to make compound pill for cattle body.