China Supply High Quality Lamivudine CAS 134678-17-4, Find details about China Lamivudine, Lamivudine Powder from Supply High Quality Lamivudine CAS 134678-17-4
Common Name | Lamivudine | ||
---|---|---|---|
CAS Number | 134678-17-4 | Molecular Weight | 229.256 |
Density | 1.7±0.1 g/cm3 | Boiling Point | 475.4±55.0 °C at 760 mmHg |
Molecular Formula | C8H11N3O3S | Melting Point | 177 ° |
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.