Product Description                                                  

_{Product Name: Saxagliptin
Synonyms:(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-tricyclo[3.3.13,7]dec-1-yl)-1-oxoethyl]-2-azabicyclo-[3.1.0]hexane-3-carbonitrile;Saxagliptin;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;BMS 477118;Onglyza;Saxagliptin(BMS 477118);Saxagliptin 15ND2;(1S,3S,5S)-2-[(2S)-2-aMino-2-(3-hydroxyadaMantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
CAS:361442-04-8
MF:C18H25N3O2
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;organic pharmaceutical;Inhibitors
Density: 1.35
Fp: 548.7ºC
Chemical Properties: White Solid
Uses: Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration an d has a pharmacokinetic profile compatible with once daily dosing .}


                                               Application                                                            

<sub>Shacketine is a type 2 diabetes drug that can stimulate the pancreas to produce more in*sulin after the meal. It was reached by the cooperation of AstraZeneca and Bristol-Myers Squibb Company and belongs to DPP-IV inhibitor. It plays the role through inhibiting GLP-l degradation. GLP-I is the hormones naturally produced in the intestine after taking food. It can regulate the secretion of in*sulin and strengthen the utilization of glucose in the peripheral tissues. The single medication of Shacketine can improve blood glucose control and the combined medication of Shacketine with metformin, sulfonylurea and thiazolidinediones can enhance curative effect. It leads to low risk of hypoglycemia and its adverse reactions are similar to placebo, showing better tolerance .

On July 31, 2009, Shakleitine tablets , a new drug of type 2 diabetes, jointly researched and developed AstraZeneca and Bristol-Myers Squibb was approved by the US FDA. It can be taken once a day to treat type 2 diabetes combined with controlling Diet and exercise. The most common side effects are upper respiratory tract infections, urinary tract infections and headaches. And other side effects include allergic reactions, such as rash and urticaria .</sub>

 

                                          Customers Reviews                                                  

_{Xi'an Tian guangyuan Biotech Co.,Ltd.}

_{Tel: 86-29-86333380}

_{Fax: 86-29-86333380}

_{Web:tgybio.en.made-in-china.com}

 
 

                                            Packing and shipping                                            

                                             Our Service                                                             
<sub>We have more than 500 vendors, we could save your effort to serve customers with supplying all your needs!

1. We has 10 years' exporting experience in active pharmaceutical ingredient products.
Our professionaland thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

1> Any inquiries will be replied within 12 hours.
2> Dedication to quality, supply & service.
3> Strictly on selecting raw materials.
4> Reasonable & competitive price, fast lead time.</sub>
 

                                       Company Information                                                 

<sub>XI'AN Tian Guangyuan Biotech Co.,Ltd.was founded in May 2003, is a professional animal and plant extracts modern and advanced enterprise object, chemical intermediates and active ingredients of natural active throughout the country, plant extracts industry, research and development, production, marketing and other areas have a strong strength.

The company is headquartered in the outskirts of Xi'an, under research and development center as well as analysis and testing center, comprehensive strength in the national forefront of the industry.
Companies rely on the wisdom and innovation of advanced technology, scientific management and all the staff and a good team spirit, will enable the company to develop a domestic industry with sik-class product quality and international competitiveness of enterprises.
Thank you for your interest in our products.</sub>

                                                       FAQ                                                                

_{1. Can I buy a sample for evaluation?} 

_{Yes, a small percentage of items are available for single-unit sample purchases online. To make it easier for our customers to locate these items, a separate section in our store will be created soon. For now, if an item offers samples, Click on the link to order the sample.}

_{2. How to make payment?} 

_{We accept payment by telegraphic transfer (T/T) and Western Union .}

_{3. How much does shipping cost?} 

_{Shipping costs vary according to the shipping method and your ship-to country. For your easy reference, the estimated shipping cost you see in your shopping cart is based on courier shipping to the United States. The system will indicate the actual shipping cost based on your selected shipping method 
and ship-to country when you checkout and before you commit to the purchase. Generally, shipping to the UK and other Western European countries is slightly more expensive than to the USA. And shipping to  Asia is slightly less expensive than to the USA.}

_{4. Does the shipping cost cover local taxes, import duties, and other import-related costs?} 

_{The shipping cost does not cover any local taxes, import duties, customs clearance, or any other import-related costs levied by your government. The buyer is responsible for these import-related costs. Please check with your local customs office for more information.}

_{5. What shipping options do I have?} 

_{In our continued effort to offer value and flexibility to our customers, we will be offering four different options to deliver your order.}

_{1-200kg Carrier express(DHL/UPS/Fedex/EMS)} 

_{300kg-500kg by air}

_{6. How long is lead time?} 

_{We deliver goods within 3 days for small order, 7-10 days for bulk order.}