China Pharmaceutical Grade 99% Chloroquine Phosphate Powder, Find details about China Chloroquine Phosphate, Chloroquine Diphosphate from Pharmaceutical Grade 99% Chloroquine Phosphate Powder
Product Name | Chloroquine Diphosphate |
CAS# | 50-63-5 |
Appearance | white crystalline powder |
Active Ingredient | Chloroquine Phosphate |
Specification | 99% Min |
Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.
Specification:
Item | Standard | Result | |||
Characters | A white or almost white crystalline powder | Conform | |||
Melting point | One melting at about 195°C | 196°C | |||
Identification | Positive | Conform | |||
Solutions | Complies with test | Conform | |||
Appearance of solution | BY5 OR GY5 max | GY5 | |||
PH(10% w/v) | 3.8-4.3 | 4.2 | |||
Related substance | one spot 1.0% max | Conform | |||
Any other spot 0.5% max | Conform | ||||
Heavy metals | 20ppm max | 10ppm | |||
Water | 2.0% max | 0.6% | |||
Assay | 98.5%~101.0% | 99.6% |
Application of chloroquine phosphate
1. Chloroquine phosphate can be used for the prevention of malaria symptoms.
2. Chloroquine phosphate can also be used for the treatment of parenteral amoebiasis, connective tissue disease, light-sensitive
diseases (such as sunburn erythema) and so on.
Certificate of Analysis
Batch Number | Z20190412001 | ||
Production Date | 2019.04.12 | ||
Batch Quantity | 80 KGS | ||
Item | Test Standard | Testing Result | |
Appearance | Powder | Complies | |
Color | White fine Powder | Complies | |
Particle Size | 100% pass 80 mesh | Complies | |
Oder | Characteristic | Complies | |
Taste | Characteristic | Complies | |
Loss on Drying | ≤5.0% | 2.20% | |
Residue on Ignition | ≤0.1% | 0.05% | |
Residual acetone | ≤0.1% | Complies | |
Residual Ethanol | ≤0.5% | Complies | |
Heave Mentals | ≤10ppm | Complies | |
Na | ≤0.1% | <0.1% | |
Pb | ≤3 ppm | Complies | |
Total Plate | <1000CFU/g | Complies | |
Yeast & Mold | <100 CFU /g | Complies | |
E. Coli | Negative | Complies | |
Salmonella | Negative | Complies | |
Conclusion: Conform with USP Standard |
Storage:Closed container. dry & cool. keep away from moisture &strong light
Shelf life:24 Months
Shipping Options as follows
EMS | Around 7-10 working days |
DHL | Around 3-5 working days |
Fedex | Around 4-6 working days |
TNT | Around 6-7 working days |
By Air | Around 5-7 working days |
By Sea | Around 15-30 working days |
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